Host Genetics, Diet, and Microbiome: The Role of AMY1
- PMID: 31056302
- DOI: 10.1016/j.tim.2019.04.001
Host Genetics, Diet, and Microbiome: The Role of AMY1
Abstract
Host gene variants selected by diet adaptation have been associated with the microbiome. Poole et al. (Cell Host Microbe 2019;25;553-564.E7) reported that AMY1 copy number, associated with obesity, also impacts microbiome composition and function. Complex genetics-diet-microbiome interactions and their effect on obesity could eventually translate into personalized nutrition.
Keywords: amylase gene; diet; microbiome.
Copyright © 2019 Elsevier Ltd. All rights reserved.
Comment on
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Human Salivary Amylase Gene Copy Number Impacts Oral and Gut Microbiomes.Cell Host Microbe. 2019 Apr 10;25(4):553-564.e7. doi: 10.1016/j.chom.2019.03.001. Cell Host Microbe. 2019. PMID: 30974084
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