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Comment
. 2019 Jun;27(6):473-475.
doi: 10.1016/j.tim.2019.04.001. Epub 2019 May 2.

Host Genetics, Diet, and Microbiome: The Role of AMY1

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Host Genetics, Diet, and Microbiome: The Role of AMY1

Sofía Morán-Ramos et al. Trends Microbiol. 2019 Jun.

Abstract

Host gene variants selected by diet adaptation have been associated with the microbiome. Poole et al. (Cell Host Microbe 2019;25;553-564.E7) reported that AMY1 copy number, associated with obesity, also impacts microbiome composition and function. Complex genetics-diet-microbiome interactions and their effect on obesity could eventually translate into personalized nutrition.

Keywords: amylase gene; diet; microbiome.

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