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Review
. 2018 Jul;10(20):168-175.
doi: 10.3126/nepjoph.v10i2.20464.

Endocannabinoid System and Ocular Vascularization

Raluca Iancu  1 , Ioana-Cristina Coman, Cosmina Barac, Mohammad Al Hammoud, Alina Popa Cherecheanu
Affiliations
Review

Endocannabinoid System and Ocular Vascularization

Raluca Iancu et al. Nepal J Ophthalmol. 2018 Jul.

Abstract

The focus of this review is the role of endocannabinoid system in ocular and systemic circulation. By critically examining preclinical and clinical research, we explore the cannabinoid receptors localization and vascular implications as well as their interaction with other anti-inflammatory drugs. The objective is to transfer knowledge on the use of cannabinoids, specifically their effect on ocular circulation and intraocular pressure, and provide a better understanding of the endocannabinoid system complexity in modulating local and systemic circulations in order to identify potential uses and limitations of cannabinoid-based therapeutics.

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