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Editorial
. 2019 May 7;139(19):2225-2227.
doi: 10.1161/CIRCULATIONAHA.119.039787.

A COmplex Cloud

Jessica L Fetterman  1 , Naomi M Hamburg  1
Affiliations
Editorial

A COmplex Cloud

Jessica L Fetterman et al. Circulation. .
No abstract available

Keywords: Editorials; carbon monoxide; cardiovascular diseases; smoking water pipes; tobacco.

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Figures

Figure.
Figure.. Vascular effects of hookah use.
Tobacco leaf–derived product is heated electronically (e-hookah) or burned using charcoal briquettes or cigarettes, resulting in a complex cloud of smoke. Tobacco toxicants in tobacco smoke lower nitric oxide (NO) activity and block vasodilation. Charcoal-heated hookah smoke has greater amounts of carbon monoxide (CO), which masks the adverse effects on vascular function, potentially by altering mitochondrial ROS signaling, activating cGMP, and activating eNOS. In aggregate, hookah smoke produced by either charcoal or e-hookah impairs vasodilator function. peNOS indicates phosphorylated endothelial nitric oxide synthase; and ROS, reactive oxygen species.
See this image and copyright information in PMC

Comment on

References

    1. Maziak W, Taleb ZB, Bahelah R, Islam F, Jaber R, Auf R, Salloum RG. The global epidemiology of waterpipe smoking. Tob Control. 2015;24(suppl 1):i3–i12. doi: 10.1136/tobaccocontrol-2014-051903 - DOI - PMC - PubMed
    1. Robinson JN, Wang B, Jackson KJ, Donaldson EA, Ryant CA. Characteristics of hookah tobacco smoking sessions and correlates of use frequency among US adults: findings from wave 1 of the Population Assessment of Tobacco and Health (PATH) Study. Nicotine Tob Res. 2018;20:731–740. doi: 10.1093/ntr/ntx060 - DOI - PubMed
    1. Doran N, Godfrey KM, Myers MG. Hookah use predicts cigarette smoking progression among college smokers. Nicotine Tob Res. 2015;17:1347–1353. doi: 10.1093/ntr/ntu343 - DOI - PubMed
    1. Castañeda G, Barnett TE, Soule EK, Young ME. Hookah smoking behavior initiation in the context of millennials. Public Health. 2016;137:124–130. doi: 10.1016/j.puhe.2016.02.013 - DOI - PMC - PubMed
    1. Shihadeh A, Schubert J, Klaiany J, El Sabban M, Luch A, Saliba NA. Toxicant content, physical properties and biological activity of waterpipe tobacco smoke and its tobacco-free alternatives. Tob Control. 2015;24(suppl 1):i22–i30. doi: 10.1136/tobaccocontrol-2014-051907 - DOI - PMC - PubMed

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