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. 2019 May;12(5):e008777.
doi: 10.1161/CIRCIMAGING.118.008777.

Early Detection of Anthracycline-Induced Cardiotoxicity in Breast Cancer Survivors With T2 Cardiac Magnetic Resonance

Maryam B Lustberg  1 , Raquel Reinbolt  1 , Daniel Addison  2 , Amy S Ruppert  3 , Sean Moore  2 , Sarah Carothers  1 , Anupama Suresh  2 , Hiranmoy Das  4 , Michael Berger  2 , Bhuvaneswari Ramaswamy  1 , Robert Wesolowski  1 , Philip Binkley  1 , Subha V Raman  2 , Charles L Shapiro  1   5
Affiliations

Early Detection of Anthracycline-Induced Cardiotoxicity in Breast Cancer Survivors With T2 Cardiac Magnetic Resonance

Maryam B Lustberg et al. Circ Cardiovasc Imaging. 2019 May.
No abstract available

Keywords: anthracyclines; breast cancer; cardiotoxicity; edema; endothelial progenitor cells; heart failure; magnetic resonance imaging.

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Figures

None
In a cohort of women with breast cancer, myocardial T2 values increased over the course of anthracycline therapy (A). One subject, for instance, had a pre-treatment T2 value of 55 ms that increased to 60ms after the first cycle and 61 ms post-treatment; while T2 then normalized to 56 ms (B-E), late gadolinium enhancement imaging after one year showed evident subepicardial scarring (F, arrow). Of note, her LV ejection fraction remained normal until 14 months when it had fallen to 47%.
See this image and copyright information in PMC

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