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Comment
. 2019 May 6;49(3):306-307.
doi: 10.1016/j.devcel.2019.04.023.

Sharing Is Caring

Qian Xue  1 , Minna Roh-Johnson  2
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Sharing Is Caring

Qian Xue et al. Dev Cell. .
Free article

Abstract

It is well known that melanoma lipid metabolism is regulated by intrinsic genetic and epigenetic changes in the cancer cells. However, recent work reveals that lipid metabolism is also controlled by the tumor microenvironment through the direct transfer of lipids from adipocytes to melanoma cells.

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  • Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins.
    Zhang M, Di Martino JS, Bowman RL, Campbell NR, Baksh SC, Simon-Vermot T, Kim IS, Haldeman P, Mondal C, Yong-Gonzales V, Abu-Akeel M, Merghoub T, Jones DR, Zhu XG, Arora A, Ariyan CE, Birsoy K, Wolchok JD, Panageas KS, Hollmann T, Bravo-Cordero JJ, White RM. Zhang M, et al. Cancer Discov. 2018 Aug;8(8):1006-1025. doi: 10.1158/2159-8290.CD-17-1371. Epub 2018 Jun 14. Cancer Discov. 2018. PMID: 29903879 Free PMC article.

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