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. 2019 Apr;24(4):1537-1550.
doi: 10.1590/1413-81232018244.16722017. Epub 2019 May 2.

[Survival rate of 10 years among women with breast cancer: a historic cohort from 2000-2014]

[Article in Portuguese]
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Free article

[Survival rate of 10 years among women with breast cancer: a historic cohort from 2000-2014]

[Article in Portuguese]
Arlene Laurenti Monterrosa Ayala et al. Cien Saude Colet. 2019 Apr.
Free article

Abstract

Breast cancer is a public health problem due to its high incidence, morbidity and mortality. The analysis of survival for this disease contributes to the description of behavior and prognostic factors. The scope of this article is to investigate survival for 10 years after diagnosis and the prognostic factors of women with breast cancer admitted to the Unified Health System Mastology Service in Joinville, State of Santa Catarina, between 2000 and 2014. A historical cohort study with data from the medical records and death certificates of 1,321 women, of whom 471 were considered eligible under the minimum follow-up criteria of 10 years (n = 288), and/or death before this period (n = 183). Survival analysis using the Kaplan-Meier model, the Log-Rank test and the Cox regression model was conducted. Overall survival at 10 years was 41% (CI 95%, 36.1%-45.0%). The risk of 10-year mortality stratified by tumor staging was higher among women with lymphatic invasion and staging II, and staging III, at 60 years or older. The findings suggest that the presence of lymphatic invasion, advanced age and intermediate/advanced staging of the disease can be considered indicators of a worse prognosis for breast cancer.

O câncer de mama é um problema de saúde pública por sua elevada incidência, morbidade e mortalidade. A análise de sobrevida dessa doença contribui para a descrição do comportamento e dos fatores prognósticos. O objetivo deste artigo é investigar a sobrevida em 10 anos após o diagnóstico, e os fatores prognósticos de mulheres com câncer de mama admitidas no Serviço de Mastologia do Sistema Único de Saúde em Joinville, Santa Catarina, entre 2000-2014. Estudo de coorte histórica com dados dos prontuários e das declarações de óbito de 1.321 mulheres, sendo que 471 foram consideradas elegíveis nos critérios tempo de acompanhamento mínimo de 10 anos (n = 288), e/ou óbito antes deste período (n = 183). Análise de sobrevida realizada pelo modelo de Kaplan-Meier, Teste de Log-Rank e Regressão de Cox. A sobrevida global em 10 anos foi 41,0% (IC95% 36,1% 45,0%). O risco de mortalidade em 10 anos estratificado pelo estadiamento tumoral foi maior entre as mulheres com invasão linfática e estadiamento II, e com 60 anos ou mais e estadiamento III. Os achados sugerem que a presença de invasão linfática,idade avançada e estadiamento intermediário/avançado da doença podem ser considerados indicadores de pior prognóstico para o câncer de mama.

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