Molecular digital data storage using DNA
- PMID: 31068682
- DOI: 10.1038/s41576-019-0125-3
Molecular digital data storage using DNA
Abstract
Molecular data storage is an attractive alternative for dense and durable information storage, which is sorely needed to deal with the growing gap between information production and the ability to store data. DNA is a clear example of effective archival data storage in molecular form. In this Review, we provide an overview of the process, the state of the art in this area and challenges for mainstream adoption. We also survey the field of in vivo molecular memory systems that record and store information within the DNA of living cells, which, together with in vitro DNA data storage, lie at the growing intersection of computer systems and biotechnology.
References
-
- Reisel, D., Gantz, J. & Rydning, J. Data age 2025: the digitization of the world from edge to core. Seagate https://www.seagate.com/files/www-content/our-story/trends/files/idc-sea... (2018).
-
- Rutten, M. G. T. A., Vaandrager, F. W., Elemans, J. A. A. W. & Nolte, R. J. M. Encoding information into polymers. Nat. Rev. Chem. 2, 365–381 (2018). - DOI
-
- Organick, L. et al. Random access in large-scale DNA data storage. Nat. Biotechnol. 36, 242–248 (2018). This study presents an end-to-end discussion of DNA data storage, demonstrating the ability to perform random access at a large scale, the first error correction that tolerates insertions and deletions, and the largest amount of digital data in DNA as of 2019. - DOI
-
- Zhirnov, V., Zadegan, R. M., Sandhu, G. S., Church, G. M. & Hughes, W. L. Nucleic acid memory. Nat. Mater. 15, 366–370 (2016). This paper presents a detailed analysis of properties of DNA as a data storage medium and compares it with other media. - DOI
-
- Stewart, K. et al. in DNA Computing and Molecular Programming (eds Doty, D. & Dietz, H.) 55–70 (Springer International Publishing, Cham, 2018).
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous
