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. 2019 Nov;47(11):1785-1798.
doi: 10.1007/s10802-019-00550-5.

Developmental Trajectories of Anxiety and Depression Symptoms from Early to Middle Childhood: a Population-Based Cohort Study in the Netherlands

Jasmijn M de Lijster  1 , Michiel A van den Dries  1   2 , Jan van der Ende  1 , Elisabeth M W J Utens  1   3   4 , Vincent W Jaddoe  2   5   6 , Gwendolyn C Dieleman  1 , Manon H J Hillegers  1 , Henning Tiemeier  1   7 , Jeroen S Legerstee  8
Affiliations

Developmental Trajectories of Anxiety and Depression Symptoms from Early to Middle Childhood: a Population-Based Cohort Study in the Netherlands

Jasmijn M de Lijster et al. J Abnorm Child Psychol. 2019 Nov.

Abstract

Developmental patterns of anxiety and depression symptoms in early childhood have previously been related to anxiety and mood disorders in middle childhood. In the current study, trajectories of anxiety and depression symptoms (1.5-10 years) were related to children's broader psychosocial and school-related functioning at 10 years. We included a population-based sample of 7499 children, for whom primary caregivers reported anxiety and depression symptoms on the Child Behavior Checklist, at children's ages of 1.5, 3, 6, and 10. Growth Mixture Modeling identified four distinct, gender-invariant, trajectories of anxiety and depression symptoms: low (82.4%), increasing (7.4%), decreasing (6.0%), and increasing symptoms up to age 6 followed by a decrease to age 10 (preschool-limited, 4.2%). Children with a non-Dutch ethnicity had lower odds to be in the increasing trajectory and higher odds to be in the decreasing and pre-school limited trajectory. Also, low maternal education predicted the decreasing and pre-school limited trajectory. Higher levels of psychopathology during pregnancy for both mothers and fathers predicted the increasing, decreasing, and preschool-limited trajectory, compared to the low trajectory. At age 10, children in the increasing and preschool-limited trajectory had diminished psychosocial outcomes (friendship-quality and self-esteem) and worse school-related outcomes (school performance and school problems). This study adds to current knowledge by demonstrating that developmental patterns of anxiety and depression symptoms in early childhood are related to broader negative outcomes in middle childhood. Child and family factors could guide monitoring of anxiety and depression symptoms in the general population and provide targets for prevention programs.

Keywords: Anxiety and depression symptoms; Developmental trajectories; Early childhood; Growth mixture modeling; Psychosocial outcomes; School outcomes.

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Conflict of interest statement

None.

Figures

Fig. 1
Fig. 1
Developmental trajectories of anxiety and depression symptoms (n = 7499)
See this image and copyright information in PMC

References

    1. Aasheim V, Waldenstrom U, Hjelmstedt A, Rasmussen S, Pettersson H, Schytt E. Associations between advanced maternal age and psychological distress in primiparous women, from early pregnancy to 18 months postpartum. BJOG: An International Journal of Obstetrics and Gynaecology. 2012;119(9):1108–1116. - PubMed
    1. Achenbach TM, Rescorla LA. Manual for the ASEBA Preschool Forms & Profiles. Burlington: University of Vermont, Research Center for Children, Youth & Families; 2000.
    1. Achenbach TM, Rescorla LA. Manual for the ASEBA school-age forms & profiles. Burlington: University of Vermont, Research Center for Children, Youth & Families: ASEBA 2001; 2001.
    1. Almquist YM. Childhood friendships and adult health: findings from the Aberdeen children of the 1950s cohort study. European Journal of Public Health. 2012;22(3):378–383. - PubMed
    1. Asparouhov T, Muthén B. Auxiliary variables in mixture modeling: 3-step approaches using Mplus. 2014. pp. 1–48.

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