Further Defining the Human Virome using NGS: Identification of Redondoviridae
- PMID: 31071291
- PMCID: PMC6849504
- DOI: 10.1016/j.chom.2019.04.010
Further Defining the Human Virome using NGS: Identification of Redondoviridae
Abstract
In this issue of Cell Host & Microbe, Abbas et al. (2019) uncover a previously undefined family of single-stranded DNA viruses, Redondoviridae, in human ororespiratory sites. The presence of Redondoviridae associates with critical illness such as respiratory failure and periodontitis, illustrating the power of metagenomics to define the human virome.
Copyright © 2019 Elsevier Inc. All rights reserved.
Comment on
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The Perioperative Lung Transplant Virome: Torque Teno Viruses Are Elevated in Donor Lungs and Show Divergent Dynamics in Primary Graft Dysfunction.Am J Transplant. 2017 May;17(5):1313-1324. doi: 10.1111/ajt.14076. Epub 2016 Nov 4. Am J Transplant. 2017. PMID: 27731934 Free PMC article.
References
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- Abbas A.A., Diamond J.M., Chehoud C., Chang B., Kotzin J.J., Young J.C., Imai I., Haas A.R., Cantu E., Lederer D.J. The perioperative lung transplant virome: torque teno viruses are elevated in donor lungs and show divergent dynamics in primary graft dysfunction. Am. J. Transplant. 2017;17:1313–1324. - PMC - PubMed
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- Abbas A.A., Taylor L.J., Dothard M.I., Leiby J.S., Fitzgerald A.S., Khatib L.A., Collman R.G., Bushman F.D. Redondoviridae, a family of small, circular DNA viruses of the human oro-respiratory tract that are associated with periodontitis and critical illness. Cell Host Microbe. 2019;25:719–729. this issue. - PMC - PubMed
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