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Comment
. 2019 Jun;40(6):465-467.
doi: 10.1016/j.it.2019.04.006. Epub 2019 May 6.

The Yellow Brick Road towards HIV Eradication

Asier Saez-Cirion  1 , Michaela Müller-Trutwin  2
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Comment

The Yellow Brick Road towards HIV Eradication

Asier Saez-Cirion et al. Trends Immunol. 2019 Jun.
Free article

Abstract

A London patient living with HIV-1 has become the second person to achieve remission from HIV-1 infection for >1 year after receiving a bone marrow stem cell transplant from a donor with cells resistant to CCR5-tropic HIV-1 infection (Gupta et al. Nature 2019;568:244-248). This case provides important clues in the uncertain path towards an HIV cure.

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  • HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation.
    Gupta RK, Abdul-Jawad S, McCoy LE, Mok HP, Peppa D, Salgado M, Martinez-Picado J, Nijhuis M, Wensing AMJ, Lee H, Grant P, Nastouli E, Lambert J, Pace M, Salasc F, Monit C, Innes AJ, Muir L, Waters L, Frater J, Lever AML, Edwards SG, Gabriel IH, Olavarria E. Gupta RK, et al. Nature. 2019 Apr;568(7751):244-248. doi: 10.1038/s41586-019-1027-4. Epub 2019 Mar 5. Nature. 2019. PMID: 30836379 Free PMC article.

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