Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 May 28;116(22):10723-10728.
doi: 10.1073/pnas.1820701116. Epub 2019 May 9.

Objecting to experiments that compare two unobjectionable policies or treatments

Affiliations

Objecting to experiments that compare two unobjectionable policies or treatments

Michelle N Meyer et al. Proc Natl Acad Sci U S A. .

Abstract

Randomized experiments have enormous potential to improve human welfare in many domains, including healthcare, education, finance, and public policy. However, such "A/B tests" are often criticized on ethical grounds even as similar, untested interventions are implemented without objection. We find robust evidence across 16 studies of 5,873 participants from three diverse populations spanning nine domains-from healthcare to autonomous vehicle design to poverty reduction-that people frequently rate A/B tests designed to establish the comparative effectiveness of two policies or treatments as inappropriate even when universally implementing either A or B, untested, is seen as appropriate. This "A/B effect" is as strong among those with higher educational attainment and science literacy and among relevant professionals. It persists even when there is no reason to prefer A to B and even when recipients are treated unequally and randomly in all conditions (A, B, and A/B). Several remaining explanations for the effect-a belief that consent is required to impose a policy on half of a population but not on the entire population; an aversion to controlled but not to uncontrolled experiments; and a proxy form of the illusion of knowledge (according to which randomized evaluations are unnecessary because experts already do or should know "what works")-appear to contribute to the effect, but none dominates or fully accounts for it. We conclude that rigorously evaluating policies or treatments via pragmatic randomized trials may provoke greater objection than simply implementing those same policies or treatments untested.

Keywords: A/B tests; field experiments; pragmatic trials; randomized controlled trials; research ethics.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1.
Fig. 1.
Results of safety checklist study and replications (studies 1 and 2). (A) Initial MTurk experiment; (B) direct replication; (C) replication with alternate vignette; (D) replication on Pollfish platform. Responses were made on a five-point scale but are presented here as percentage of participants who chose “very inappropriate” or “somewhat inappropriate,” to reflect the rate of disapproval.
Fig. 2.
Fig. 2.
Disapproval of experiments not explained primarily by joint evaluation or aversion to randomization. (A) study 4, MTurk; (B) study 5, MTurk; (C) study 5, Pollfish.
Fig. 3.
Fig. 3.
Results of safety checklist and drug effectiveness replications in healthcare clinicians (study 6). (A) safety checklist; (B) drug effectiveness.

Comment in

References

    1. Baldassarri D, Abascal M (2017) Field experiments across the social sciences. Annu Rev Sociol 43:41–73.
    1. Haynes L, Service O, Goldacre B, Torgerson D (2012) Test, learn, adapt: Developing public policy with randomised controlled trials (Cabinet Office Behavioural Insights Team, London). Available at https://assets.publishing.service.gov.uk/government/uploads/system/uploa.... Accessed December 8, 2018.
    1. Greiner DJ, Pattanayak CW (2012) Randomized evaluation in legal assistance: What difference does representation (offer and actual use) make? Yale Law J 121:2118–2214.
    1. Institute of Medicine Roundtable on Evidence-Based Medicine (2007) The Learning Healthcare System: Workshop Summary, eds Olsen L, Aisner D, McGinnis JM. Olsen L, Aisner D, McGinnis JM (National Academies Press, Washington, DC: ). - PubMed
    1. Connolly P, Biggart A, Miller S, O’Hare L, Thurston A (2017) Using Randomised Controlled Trials in Education (Sage, London: ).

MeSH terms

LinkOut - more resources