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Comment
. 2019 Jun 3;151(6):705.
doi: 10.1085/jgp.201912385. Epub 2019 May 10.

CFTR gets together

Caitlin Sedwick
Comment

CFTR gets together

Caitlin Sedwick. J Gen Physiol. .

Abstract

JGP study shows that pro-secretory agonists prompt CFTR to assemble into large lipid platforms.

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Figures

None
First author Asmahan Abu-Arish (left), senior author John Hanrahan (right), and colleagues show that agonists that stimulate secretion cause CFTR to assemble into large, ceramide-rich platforms on the surface of airway epithelial cells (outlined area in micrograph).
See this image and copyright information in PMC

Comment on

References

    1. Abu-Arish A., et al. J. Gen. Physiol. 2019 doi: 10.1085/jgp.201812143. - DOI - PMC - PubMed
    1. Dudez T., et al. . 2008. Cell Res. 1783:779–788. - PubMed
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    1. Abu-Arish A., et al. . 2015. Biophys. J. 109:85–94. - PMC - PubMed
    1. Chappe F., et al. . 2008. J. Pharmacol. Exp. Ther. 327:226–238. - PubMed

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