Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Feb;22(1):22-32.
doi: 10.1007/s11307-019-01366-x.

Research Progress of [68Ga]Citrate PET's Utility in Infection and Inflammation Imaging: a Review

Tingting Xu  1 , Yue Chen  2   3
Affiliations
Review

Research Progress of [68Ga]Citrate PET's Utility in Infection and Inflammation Imaging: a Review

Tingting Xu et al. Mol Imaging Biol. 2020 Feb.

Abstract

Imaging diagnosis of infection and inflammation has been challenging for many years. Infection imaging agents commonly used in nuclear medicine, such as [67Ga]citrate, 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG), and radionuclide-labeled leukocytes, have their own shortcomings. Identification of a tracer with considerable economic benefit, high specificity, and low radiation dose has become clinically urgent. In the twenty-first century, with the increasing availability of positron emission tomography (PET) devices and the commercialization of Ge-68/Ga-68 generators, the study of [68Ga]citrate applications for infection and inflammation has increased and shown good potential. In this report, the research progress that supports [68Ga]citrate PET's applications various infectious diseases and inflammation is reviewed.

Keywords: Infection; Inflammation; Utility; [68Ga]citrate PET.

PubMed Disclaimer

References

    1. Intern Med J. 2019 Aug;49(8):1016-1022 - PubMed
    1. Chin J Cancer. 2010 Apr;29(4):451-5 - PubMed
    1. Eur Radiol. 2000;10(11):1815-23 - PubMed
    1. Contrast Media Mol Imaging. 2018 Feb 25;2018:9892604 - PubMed
    1. Nucl Med Biol. 2011 Apr;38(3):393-8 - PubMed

Publication types

LinkOut - more resources