Heterozygosity for the Alpha-1-Antitrypsin Z Allele in Cirrhosis Is Associated With More Advanced Disease

David Stephen Prince^{1

2}, Ken Liu^{3

4}, Geoffrey William McCaughan^{3

4}, James Kench^{3

5}, Simone Irene Strasser^{3

4}

Affiliations

¹ Department of Gastroenterology, Liverpool Hospital, Sydney, New South Wales, Australia.
² South Western Sydney Clinical School, University of New South Wales, Sydney, Australia.
³ A. W. Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, Australia.
⁴ Sydney Medical School, University of Sydney, Sydney, Australia.
⁵ Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Sydney, Australia.

Comment

David Stephen Prince et al. Liver Transpl. 2019 Aug.

. 2019 Aug;25(8):1285-1286.

doi: 10.1002/lt.25487. Epub 2019 Jun 25.

David Stephen Prince^{1

2}, Ken Liu^{3

4}, Geoffrey William McCaughan^{3

4}, James Kench^{3

5}, Simone Irene Strasser^{3

4}

¹ Department of Gastroenterology, Liverpool Hospital, Sydney, New South Wales, Australia.
² South Western Sydney Clinical School, University of New South Wales, Sydney, Australia.
³ A. W. Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, Australia.
⁴ Sydney Medical School, University of Sydney, Sydney, Australia.
⁵ Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Sydney, Australia.

No abstract available

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Schaefer B, Finkenstedt A, Effenberger M, Viveiros A, Tilg H, Zoller H. Schaefer B, et al. Liver Transpl. 2019 Aug;25(8):1287-1288. doi: 10.1002/lt.25500. Epub 2019 Jun 25. Liver Transpl. 2019. PMID: 31120619 No abstract available.

Heterozygosity for the alpha-1-antitrypsin Z allele in cirrhosis is associated with more advanced disease.
Schaefer B, Mandorfer M, Viveiros A, Finkenstedt A, Ferenci P, Schneeberger S, Tilg H, Zoller H. Schaefer B, et al. Liver Transpl. 2018 Jun;24(6):744-751. doi: 10.1002/lt.25057. Epub 2018 May 14. Liver Transpl. 2018. PMID: 29573137 Free PMC article.