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Comment
. 2019 Jun 4;116(11):2060-2061.
doi: 10.1016/j.bpj.2019.04.027. Epub 2019 May 2.

May the Road Rise to Meet You: DNA Deformation May Drive DNA Translocation

Paul J Jardine  1
Affiliations
Comment

May the Road Rise to Meet You: DNA Deformation May Drive DNA Translocation

Paul J Jardine. Biophys J. .
No abstract available

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Figures

Figure 1
Figure 1
Architecture of a viral DNA packaging motor. In all dsDNA phages and the herpesviruses, a dodecameric portal protein is embedded in a unique fivefold vertex of the head shell. In the well-studied bacteriophage φ29, the pentameric packaging ATPase (blue) is anchored to the capsid through the pentameric prohead RNA (pRNA) scaffold (magenta) and pushes DNA through the dodecameric connector portal (cyan). pRNA is not found in other systems, with the ATPase making direct contact with the portal and/or the head shell. Reprinted from Mao et al. (13) with permission from Elsevier.
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