Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 May 13:25:3537-3541.
doi: 10.12659/MSM.916475.

Recent Advances in the Surgical Treatment of Advanced Gastric Cancer: A Review

Affiliations
Review

Recent Advances in the Surgical Treatment of Advanced Gastric Cancer: A Review

Zhaoyang Tan. Med Sci Monit. .

Abstract

d_abstr_R Gastric cancer is a common malignancy with a poor prognosis, and surgical treatment remains the first-line approach to treatment to provide a cure. Despite advances in surgical techniques, radiotherapy, chemotherapy, and neoadjuvant therapy, gastric cancer remains the second leading cause of cancer death worldwide. Although the 5-year survival rate of early gastric cancer can reach >90%, due to the low early diagnosis rate, most patients present with advanced-stage gastric cancer. Therefore, there has been increasing interest in improving surgical treatment of advanced gastric cancer. Lymph node dissection is an important part of the surgical treatment of advanced gastric cancer due to the high incidence of lymph node metastasis. Although prospective studies have confirmed the safety and feasibility of laparoscopic surgery for early gastric cancer, the relevant treatment models of advanced gastric cancer still need to be further explored and validated. This review aims to provide an update on the recent advances in the surgical treatment of advanced gastric cancer.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest

None.

Similar articles

Cited by

References

    1. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2019. Cancer J Clin. 2019;69(1):7–34. - PubMed
    1. Zhang XY, Zhang PY. Gastric cancer: Somatic genetics as a guide to therapy. J Med Genet. 2017;54(5):305–12. - PubMed
    1. Digklia A, Wagner AD. Advanced gastric cancer: Current treatment landscape and future perspectives. World J Gastroenterol. 2016;22(8):2403–14. - PMC - PubMed
    1. Sun Z, Wang Q, Yu X, et al. Risk factors associated with splenic hilar lymph node metastasis in patients with advanced gastric cancer in northwest China. Int J Clin Exp Med. 2015;8(11):21358–64. - PMC - PubMed
    1. Obermannova R, Lordick F. Insights into next developments in advanced gastric cancer. Curr Opin Oncol. 2016;28(4):367–75. - PubMed