A Review of Extraintestinal Manifestations and Complications of Inflammatory Bowel Disease
- PMID: 31080385
- PMCID: PMC6503692
- DOI: 10.4103/sjmms.sjmms_81_18
A Review of Extraintestinal Manifestations and Complications of Inflammatory Bowel Disease
Abstract
Extraintestinal manifestations (EIMs) are common in inflammatory bowel disease (IBD), in both Crohn's disease and ulcerative colitis. Almost any organ system can be affected, including the musculoskeletal, dermatologic, renal, hepatopancreatobiliary, pulmonary and ocular systems. However, the musculoskeletal and dermatologic systems are the most commonly involved sites of manifestations. While some manifestations such as peripheral arthritis and erythema nodosum have an association with IBD activity, others such as axial arthropathy, pyoderma gangrenosum and primary sclerosing cholangitis have an independent disease course. This review provides a summary of the most common EIMs in IBD and their prevalence and management.
Keywords: Extraintestinal manifestations; arthritis; erythema nodosum; inflammatory bowel disease; osteoporosis; primary sclerosing cholangitis.
Conflict of interest statement
There are no conflicts of interest.
References
-
- Ott C, Schölmerich J. Extraintestinal manifestations and complications in IBD. Nat Rev Gastroenterol Hepatol. 2013;10:585–95. - PubMed
-
- Vavricka SR, Brun L, Ballabeni P, Pittet V, Prinz Vavricka BM, Zeitz J, et al. Frequency and risk factors for extraintestinal manifestations in the Swiss inflammatory bowel disease cohort. Am J Gastroenterol. 2011;106:110–9. - PubMed
-
- Rudwaleit M, van der Heijde D, Landewé R, Listing J, Akkoc N, Brandt J, et al. The development of assessment of spondyloArthritis international society classification criteria for axial spondyloarthritis (part II): Validation and final selection. Ann Rheum Dis. 2009;68:777–83. - PubMed
-
- Peeters H, Vander Cruyssen B, Mielants H, de Vlam K, Vermeire S, Louis E, et al. Clinical and genetic factors associated with sacroiliitis in Crohn's disease. J Gastroenterol Hepatol. 2008;23:132–7. - PubMed