Brexanolone
- PMID: 31082098
- Bookshelf ID: NBK541054
Brexanolone
Excerpt
Brexanolone is a medication used in the treatment of postpartum depression in adult women. It is in the GABA-A modulator class of medications. This activity describes the indications, contraindications, pharmacodynamics, pharmacokinetics, and monitoring for brexanolone as a valuable agent in treating postpartum depression. This activity reviews information for brexanolone pertinent for members of the interprofessional team in the treatment of patients with postpartum depression.
Copyright © 2025, StatPearls Publishing LLC.
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References
-
- Schmied V, Johnson M, Naidoo N, Austin MP, Matthey S, Kemp L, Mills A, Meade T, Yeo A. Maternal mental health in Australia and New Zealand: a review of longitudinal studies. Women Birth. 2013 Sep;26(3):167-78. - PubMed
-
- Gavin NI, Gaynes BN, Lohr KN, Meltzer-Brody S, Gartlehner G, Swinson T. Perinatal depression: a systematic review of prevalence and incidence. Obstet Gynecol. 2005 Nov;106(5 Pt 1):1071-83. - PubMed
-
- Noorlander Y, Bergink V, van den Berg MP. Perceived and observed mother-child interaction at time of hospitalization and release in postpartum depression and psychosis. Arch Womens Ment Health. 2008;11(1):49-56. - PubMed