Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 May;62(3):328-335.
doi: 10.3340/jkns.2019.0026. Epub 2019 May 1.

Epilepsy Surgery in Children versus Adults

Ki Hyeong Lee  1 , Yun-Jin Lee  1   2 , Joo Hee Seo  1 , James E Baumgartner  1 , Michael Westerveld  1
Affiliations

Epilepsy Surgery in Children versus Adults

Ki Hyeong Lee et al. J Korean Neurosurg Soc. 2019 May.

Abstract

Epilepsy is one of the most common chronic neurological disorder affecting 6-7 per 1000 worldwide. Nearly one-third of patients with newly diagnosed epilepsy continue to have recurrent seizures despite adequate trial of more than two anti-seizure drugs : drug-resistant epilepsy (DRE). Children with DRE often experience cognitive and psychosocial co-morbidities requiring more urgent and aggressive treatment than adults. Epilepsy surgery can result in seizure-freedom in approximately two-third of children with improvement in cognitive development and quality of life. Understanding fundamental differences in etiology, co-morbidity, and neural plasticity between children and adults is critical for appropriate selection of surgical candidates, appropriate presurgical evaluation and surgical approach, and improved overall outcome.

Keywords: Child; Drug resistant epilepsy; Epilepsy; Surgery.

PubMed Disclaimer

Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

References

    1. Abdel-Mannan O, Taylor H, Donner EJ, Sutcliffe AG. A systematic review of sudden unexpected death in epilepsy (SUDEP) in childhood. Epilepsy Behav. 2019;90:99–106. - PubMed
    1. Baba H, Toda K, Ono T, Honda R, Baba S. Surgical and developmental outcomes of corpus callosotomy for West syndrome in patients without MRI lesions. Epilepsia. 2018;59:2231–2239. - PubMed
    1. Bartoli A, El Hassani Y, Jenny B, Momjian S, Korff CM, Seeck M, et al. What to do in failed hemispherotomy? Our clinical series and review of the literature. Neurosurgical Rev. 2018;41:125–132. - PubMed
    1. Baulac S, Ishida S, Marsan E, Miquel C, Biraben A, Nguyen DK, et al. Familial focal epilepsy with focal cortical dysplasia due to DEPDC5 mutations. Ann Neurol. 2015;77:675–683. - PubMed
    1. Britton JW. Electrical stimulation mapping with stereo-EEG electrodes. J Clin Neurophysiol. 2018;35:110–114. - PubMed

LinkOut - more resources