Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2019 Apr;92(2):195-199.
doi: 10.15386/cjmed-1030. Epub 2019 Apr 25.

Kimura disease: case report and brief review of literature

Harshi Dhingra  1 , Ruchi Nagpal  2 , Asif Baliyan  3 , Sathyavathi R Alva  4
Affiliations
Case Reports

Kimura disease: case report and brief review of literature

Harshi Dhingra et al. Med Pharm Rep. 2019 Apr.

Abstract

Kimura disease is a rare chronic inflammatory disorder of unknown cause, primarily seen in young Asian males. The disease is characterized by painless subcutaneous swelling, blood and tissue eosinophilia and raised IgE levels. Early diagnosis of Kimura's disease may spare the patient from unnecessary invasive diagnostic procedure. We describe a case of Kimura disease in a 14-year old male presenting with left submandibular swelling and also provide a brief review of the literature.

Keywords: IgE; Kimura disease; eosinophilia.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Polymorphous population of lymphoid cells with eosinophils (MGG stain, 40X).
Figure 2
Figure 2
Gross image of the homogenous grey white cut surface of the lymph node.
Figure 3
Figure 3
Hyperplastic follicles with germinal centers (H&E stain, 10X).
Figure 4
Figure 4
Germinal center infiltrated by eosinophils and histiocytes (H&E, 40X).
Figure 5
Figure 5
Prominent eosinophilic infiltrate with microabscess formation (H&E stain, 10X).
Figure 6
Figure 6
Endothelial cell proliferation with lumen containing RBCs in the medulla (H&E stain, 40X).
See this image and copyright information in PMC

References

    1. Ioachim H, Ratech H. Kimura lymphadenopathy. In: Ioachim H, Ratech H, editors. Ioachim’s Lymph Node Pathology. 3rd ed. Philadelphia: Lippincott-Raven; 2002. pp. 209–11.
    1. Abhange RS, Jadhav RP, Jain NK. Kimura disease: A rare case report. Ann Pathol Lab Med. 2018;5:53–55.
    1. Rajesh A, Prasanth T, Naga Sirisha VC, Azmi M. Kimura’s disease: A case presentation of postauricular swelling. Niger J Clin Pract. 2016;19:827–830. - PubMed
    1. Tseng CF, Lin HC, Huang SC, Su YC. Kimura’s disease presenting as bilateral parotid masses. Eur Arch of Otorhinolaryngol. 2005;262:8–10. - PubMed
    1. Fouda MA, Gheith O, Refaie A, El-Saeed M, Bakr A, Wafa E, et al. Kimura disease: a case report and review of the literature with a new management protocol. Int J Nephrol. 2011;2010 673908. - PMC - PubMed

Publication types

LinkOut - more resources