Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Sep;14(9):1643-1650.
doi: 10.4103/1673-5374.255995.

Knowledge domain and emerging trends in Alzheimer's disease: a scientometric review based on CiteSpace analysis

Affiliations

Knowledge domain and emerging trends in Alzheimer's disease: a scientometric review based on CiteSpace analysis

Shuo Liu et al. Neural Regen Res. 2019 Sep.

Abstract

Alzheimer's disease is the most common cause of dementia. It is an increasingly serious global health problem and has a significant impact on individuals and society. However, the precise cause of Alzheimer's disease is still unknown. In this study, 11,748 Web-of-Science-indexed manuscripts regarding Alzheimer's disease, all published from 2015 to 2019, and their 693,938 references were analyzed. A document co-citation network map was drawn using CiteSpace software. Research frontiers and development trends were determined by retrieving subject headings with apparent changing word frequency trends, which can be used to forecast future research developments in Alzheimer's disease.

Keywords: Alzheimer's disease; CiteSpace; Web of Science; mapping knowledge domain; nerve regeneration; neural regeneration; neuroprotection.

PubMed Disclaimer

Conflict of interest statement

None

Figures

Figure 1
Figure 1
Time sequence of relevant papers on Alzheimer’s disease published from 1991 to 2019 in Web of Science.
Figure 2
Figure 2
Co-authorship of Alzheimer’s disease research. The most representative author is the Alzheimer’s Disease Neuroimaging Initiative.
Figure 3
Figure 3
Co-institutes in the field of Alzheimer’s disease. University College London from United Kingdom publishes the largest number of studies.
Figure 4
Figure 4
Co-countries in the field of Alzheimer’s disease.
Figure 5
Figure 5
Analysis of co-occurring keywords in Alzheimer’s disease research. Microglia is the focus of research.
Figure 6
Figure 6
Recurring Alzheimer’s disease research after Figure 5 data are sorted into chronological order.
Figure 7
Figure 7
Document co-citation analysis in Alzheimer’s disease research. Mckhann et al. (2011) has the largest number of citations.

References

    1. Abud EM, Ramirez RN, Martinez ES, Healy LM, Nguyen CHH, Newman SA, Yeromin AV, Scarfone VM, Marsh SE, Fimbres C, Caraway CA, Fote GM, Madany AM, Agrawal A, Kayed R, Gylys KH, Cahalan MD, Cummings BJ, Antel JP, Mortazavi A. iPSC-derived human microglia-like cells to study neurological diseases. Neuron. 2017;94:278–293 e279. - PMC - PubMed
    1. Albert MS, DeKosky ST, Dickson D, Dubois B, Feldman HH, Fox NC, Gamst A, Holtzman DM, Jagust WJ, Petersen RC, Snyder PJ, Carrillo MC, Thies B, Phelps CH. The diagnosis of mild cognitive impairment due to Alzheimer’s disease: recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease. Alzheimers Dement. 2011;7:270–279. - PMC - PubMed
    1. Alzheimer A. Über eine eigenartige Erkrankung der Hirnrinde. Allgemeine Zeitschrift für Psychiatrie und Psychisch-Gerichtlich Medizin. 1907;64:146–148.
    1. Arber C, Lovejoy C, Wray S. Stem cell models of Alzheimer’s disease: progress and challenges. Alzheimers Res Ther. 2017;9:42. - PMC - PubMed
    1. Avramopoulos D. Genetics of Alzheimer’s disease: recent advances. Genome Med. 2009;1:34. - PMC - PubMed

LinkOut - more resources