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. 2019 Dec;54(12):1973-1986.
doi: 10.1038/s41409-019-0554-9. Epub 2019 May 14.

Advances in hematopoietic stem cell transplantation in the Asia-Pacific region: the second report from APBMT 2005-2015

Minako Iida  1 , Yoshihisa Kodera  2 , Anthony Dodds  3 , Aloysius Yew Leng Ho  4 , Ian Nivison-Smith  5 , Mafruha Rumana Akter  6 , Tong Wu  7 , Albert Kwok Wai Lie  8 , Ardeshir Ghavamzadeh  9 , Hyoung Jin Kang  10 , Tee Chuan Ong  11 , Aye Aye Gyi  12 , Tasneem Farzana  13 , Honorata Baylon  14 , Lallindra Gooneratne  15 , Jih-Luh Tang  16 , Udomsak Bunworasate  17 , Van Man Huynh  18 , Alok Srivastava  19 , Shinichiro Okamoto  20 , Yoshiko Atsuta  21 ; Registry Committee of the Asia-Pacific Blood and Marrow Transplantation Group (APBMT)
Affiliations

Advances in hematopoietic stem cell transplantation in the Asia-Pacific region: the second report from APBMT 2005-2015

Minako Iida et al. Bone Marrow Transplant. 2019 Dec.

Erratum in

Abstract

Between 2005 and 2015, 138,165 hematopoietic stem cell transplantation (HSCT) were reported in 18 countries/regions in the Asia-Pacific region. In this report, we describe current trends in HSCT throughout the Asia-Pacific region and differences among nations in this region and various global registries. Since 2008, more than 10,000 HSCTs have been recorded each year by the Asia-Pacific Blood and Marrow Transplantation Group Data Center. Between 2005 and 2015, the greatest increase in the number of HSCTs was observed in Vietnam. Allogeneic HSCT was performed more frequently than autologous HSCT, and a majority of cases involved related donors. Regarding allogeneic HSCT, the use of cord blood has remained steady, especially in Japan, and the number of cases involving related HLA non-identical donors has increased rapidly, particularly in China. The incidence of hemoglobinopathy, a main indication for allogeneic HSCT in India, China, Iran, and Pakistan, increased nearly six-fold over the last decade. Among the 18 participating countries/regions, the transplant rate per population varied widely according to the absolute number of HSCTs and the national/regional population size. We believe that this report will not only benefit the AP region but will also provide information about HSCT to other regions worldwide.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
a Number of hematopoietic stem cell transplants (HSCTs) performed between 2006 and 2015 by transplant type. b Proportions of autologous and allogeneic HSCTs performed in 2015 by country/region
Fig. 2
Fig. 2
Trends in the number of hematopoietic stem cell transplants (HSCTs) by donor type
Fig. 3
Fig. 3
The number of hematopoietic stem cell transplants (HSCTs) by disease. a Diseases associated with more than 200 HSCTs or b fewer than 200 HSCTs in 2006
Fig. 4
Fig. 4
Correlation between absolute numbers of transplants and the gross domestic product (GDP, top) and (bottom)
See this image and copyright information in PMC

References

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    1. Yoshimi A, Suzuki R, Atsuta Y, Iida M, Lu DP, Tong W, et al. Hematopoietic SCT activity in Asia: a report from the Asia-Pacific Blood and Marrow Transplantation Group. Bone Marrow Transpl. 2010;45:1682–91. doi: 10.1038/bmt.2010.34. - DOI - PubMed
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