Pembrolizumab combined with lenalidomide and low-dose dexamethasone for relapsed or refractory multiple myeloma: phase I KEYNOTE-023 study
- PMID: 31090915
- DOI: 10.1111/bjh.15946
Pembrolizumab combined with lenalidomide and low-dose dexamethasone for relapsed or refractory multiple myeloma: phase I KEYNOTE-023 study
Keywords: dexamethasone; lenalidomide; multiple myeloma; pembrolizumab; relapsed/refractory.
References
REFERENCES
-
- Ahamadi, M., Freshwater, T., Prohn, M., Li, C.H., De Alwis, D.P., de Greef, R., Elassaiss-Schaap, J., Kondic, A. & Stone, J.A. (2016) Model-based characterization of the pharmacokinetics of pembrolizumab: a humanized anti-PD-1 monoclonal antibody in advanced solid tumors. CPT: Pharmacometrics & Systems Pharmacology, 6, 49-57.
-
- The ASCO Post (2017) FDA places clinical hold on three studies evaluating pembrolizumab in multiple myeloma. http://www.ascopost.com/News/57813. Accessed 5 February 2019.
-
- Badros, A., Hyjek, E., Ma, N., Lesokhin, A., Dogan, A., Rapoport, A.P., Kocoglu, M., Lederer, E., Philip, S., Milliron, T., Dell, C., Goloubeva, O. & Singh, Z. (2017) Pembrolizumab, pomalidomide and low dose dexamethasone for relapsed/refractory multiple myeloma. Blood, 130, 1189-1197.
-
- Durie, B.G.M., Harousseau, J.L., Miguel, J.S., Blade, J., Barlogie, B., Anderson, K., Gertz, M., Dimopoulos, M., Westin, J., Sonneveld, P., Ludwig, H., Gahrton, G., Beksac, M., Crowley, J., Belch, A., Boccadaro, M., Turesson, I., Joshua, D., Vesole, D., Kyle, R., Alexanian, R., Tricot, G., Attal, M., Merlini, G., Powles, R., Richardson, P., Shimizu, K., Tosi, P., Morgan, G. & Rajkumar, S.V.; on behalf of the International Myeloma Working Group. (2006) International uniform response criteria for multiple myeloma. Leukemia, 20, 1467-1473.
-
- Gorgun, G., Samur, M.K., Cowens, K.B., Paula, S., Bianchi, G., Anderson, J.E., White, R.E., Singh, A., Ohguchi, H., Suzuki, R., Kikuchi, S., Harada, T., Hideshima, T., Tai, Y.T., Laubach, J.P., Raje, N., Magrangeas, F., Minvielle, S., Avet-Loiseau, H., Munshi, N.C., Dorfman, D.M., Richardson, P.G. & Anderson, K.C. (2015) Lenalidomide enhances immune checkpoint blockade-induced immune response in multiple myeloma. Clinical Cancer Research, 21, 4607-4618.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
