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Case Reports
. 2019 Apr 8:2019:4076740.
doi: 10.1155/2019/4076740. eCollection 2019.

Macular Rash, Thrombocytopenia, and Hyperbilirubinemia in a Preterm Infant

Nurin Chatur  1 , Marina Castro  2 , Kin Fan Young Tai  2
Affiliations
Case Reports

Macular Rash, Thrombocytopenia, and Hyperbilirubinemia in a Preterm Infant

Nurin Chatur et al. Case Rep Pediatr. .

Abstract

Neonatal hyperthyroidism is usually caused by the passage of maternal thyroid receptor antibodies. This relatively rare condition has various manifestations including cholestasis, prematurity, and cardiomegaly. We present a case of a preterm infant with neonatal Graves' disease who presented with cholestasis, cardiomegaly, and a macularpapular rash that was thought to be suspicious for congenital infection. This case has been reported to illustrate lessons learnt for early identification of a neonate with Graves' disease in order to expedite treatment.

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Figures

Figure 1
Figure 1
Photographs of the neonate's diffuse macular rash.
See this image and copyright information in PMC

References

    1. Polak M., Legac I., Vuillard E., Guibourdenche J., Castanet M., Luton D. Congenital hyperthyroidism: the fetus as a patient. Hormone Research in Paediatrics. 2006;65(5):235–242. doi: 10.1159/000092454. - DOI - PubMed
    1. Besançon A., Beltrand J., Le Gac I., Luton D., Polak M. Management of neonates born to women with Graves’ disease: a cohort study. European Journal of Endocrinology. 2014;170(6):855–862. doi: 10.1530/eje-13-0994. - DOI - PubMed
    1. van der Kaay D. C. M., Wasserman J. D., Palmert M. R. Management of neonates born to mothers with Graves disease. Pediatrics. 2016;137(4) doi: 10.1542/peds.2015-1878.e20151878 - DOI - PubMed
    1. Caroll D., Kamath P., Stewart L. Congenital viral infection? The Lancet. 2005;365(9464):p. 1110. doi: 10.1016/S0140-6736(05)71149-1. - DOI - PubMed
    1. Oglivy-Stuart A. L. Neonatal thyroid disorders. Archives of Disease in Childhood—Fetal and Neonatal Edition. 2002;87(3):165–171. doi: 10.1136/fn.87.3.f165. - DOI - PMC - PubMed

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