Aiming at Cancer In Vivo: Ferroptosis-Inducer Delivered by Nanoparticles
- PMID: 31100261
- PMCID: PMC6936732
- DOI: 10.1016/j.chembiol.2019.05.002
Aiming at Cancer In Vivo: Ferroptosis-Inducer Delivered by Nanoparticles
Abstract
Induction of ferroptosis has emerged as a potential cancer therapeutic approach. In this issue of Cell Chemical Biology, Zhang et al. (2019) demonstrate the anticancer efficacy and safety of the ferroptosis inducer imidazole ketone erastin (IKE) in a xenograft model by using a nanoparticle-based delivery system.
Copyright © 2019 Elsevier Ltd. All rights reserved.
Comment on
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Imidazole Ketone Erastin Induces Ferroptosis and Slows Tumor Growth in a Mouse Lymphoma Model.Cell Chem Biol. 2019 May 16;26(5):623-633.e9. doi: 10.1016/j.chembiol.2019.01.008. Epub 2019 Feb 21. Cell Chem Biol. 2019. PMID: 30799221 Free PMC article.
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