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Editorial
. 2019;8(1):153-154.
doi: 10.1016/j.jcmgh.2019.04.006. Epub 2019 May 15.

NO to Lysosomes: A Signal for Insulin Resistance in Obesity

Ali Javaheri  1 , Abhinav Diwan  2
Affiliations
Editorial

NO to Lysosomes: A Signal for Insulin Resistance in Obesity

Ali Javaheri et al. Cell Mol Gastroenterol Hepatol. 2019.
No abstract available

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Comment on

  • Hepatic Lysosomal iNOS Activity Impairs Autophagy in Obesity.
    Qian Q, Zhang Z, Li M, Savage K, Cheng D, Rauckhorst AJ, Ankrum JA, Taylor EB, Ding WX, Xiao Y, Cao HJ, Yang L. Qian Q, et al. Cell Mol Gastroenterol Hepatol. 2019;8(1):95-110. doi: 10.1016/j.jcmgh.2019.03.005. Epub 2019 Mar 27. Cell Mol Gastroenterol Hepatol. 2019. PMID: 30926581 Free PMC article.

References

    1. Qian Q., Zhang Z., Li M., Savage K., Cheng D., Rauckhorst A.J., Ankrum J.A., Taylor E.B., Ding W-x, Xiao Y., Cao H-j, Yang L. Hepatic lysosomal iNOS activity impairs autophagy in obesity. Cell Mol Gastroenterol Hepatol. 2019;8:95–110. - PMC - PubMed
    2. Qian Q, Zhang Z, Li M, Savage K, Cheng D, Rauckhorst AJ, Ankrum JA, Taylor EB, Ding W-x, Xiao Y, Cao H-j, Yang L. Hepatic lysosomal iNOS activity impairs autophagy in obesity. Cell Mol Gastroenterol Hepatol 2019;8:95–110. - PMC - PubMed
    1. Qian Q., Zhang Z., Orwig A., Chen S., Ding W.X., Xu Y., Kunz R.C., Lind N.R.L., Stamler J.S., Yang L. S-nitrosoglutathione reductase dysfunction contributes to obesity-associated hepatic insulin resistance via regulating autophagy. Diabetes. 2018;67:193–207. - PMC - PubMed
    2. Qian Q, Zhang Z, Orwig A, Chen S, Ding WX, Xu Y, Kunz RC, Lind NRL, Stamler JS, Yang L. S-nitrosoglutathione reductase dysfunction contributes to obesity-associated hepatic insulin resistance via regulating autophagy. Diabetes 2018;67:193-207. - PMC - PubMed
    1. Jia L., Wang Y., Wang Y., Ma Y., Shen J., Fu Z., Wu Y., Su S., Zhang Y., Cai Z., Wang J., Xiang M. Heme oxygenase-1 in macrophages drives septic cardiac dysfunction via suppressing lysosomal degradation of inducible nitric oxide synthase. Circ Res. 2018;122:1532–1544. - PubMed
    2. Jia L, Wang Y, Wang Y, Ma Y, Shen J, Fu Z, Wu Y, Su S, Zhang Y, Cai Z, Wang J, Xiang M. Heme oxygenase-1 in macrophages drives septic cardiac dysfunction via suppressing lysosomal degradation of inducible nitric oxide synthase. Circ Res 2018;122:1532-1544. - PubMed
    1. Liu H., Javaheri A., Godar R.J., Murphy J., Ma X., Rohatgi N., Mahadevan J., Hyrc K., Saftig P., Marshall C., McDaniel M.L., Remedi M.S., Razani B., Urano F., Diwan A. Intermittent fasting preserves beta-cell mass in obesity-induced diabetes via the autophagy-lysosome pathway. Autophagy. 2017;13:1952–1968. - PMC - PubMed
    2. Liu H, Javaheri A, Godar RJ, Murphy J, Ma X, Rohatgi N, Mahadevan J, Hyrc K, Saftig P, Marshall C, McDaniel ML, Remedi MS, Razani B, Urano F, Diwan A. Intermittent fasting preserves beta-cell mass in obesity-induced diabetes via the autophagy-lysosome pathway. Autophagy 2017;13:1952-1968. - PMC - PubMed
    1. Ma X., Mani K., Liu H., Kovacs A., Murphy J.T., Foroughi L., French B.A., Weinheimer C.J., Kraja A., Benjamin I.J., Hill J.A., Javaheri A., Diwan A. Transcription factor EB activation rescues advanced alphaB-crystallin mutation-induced cardiomyopathy by normalizing desmin localization. JAMA. 2019;8:e010866. - PMC - PubMed
    2. Ma X, Mani K, Liu H, Kovacs A, Murphy JT, Foroughi L, French BA, Weinheimer CJ, Kraja A, Benjamin IJ, Hill JA, Javaheri A, Diwan A. Transcription factor EB activation rescues advanced alphaB-crystallin mutation-induced cardiomyopathy by normalizing desmin localization. JAMA 2019;8:e010866. - PMC - PubMed

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