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. 2019;12(3):281-290.
doi: 10.1159/000499387. Epub 2019 May 17.

The Amount of Weight Loss Six Months after Bariatric Surgery: It Makes a Difference

Olga Nedeljkovic-Arsenovic  1 , Marko Banovic  2   3 , Dejan Radenkovic  2   4 , Nemanja Rancic  5 , Snezana Polovina  6   7 , Dragan Micic  2   6 , Ivana Nedeljkovic  2   3
Affiliations

The Amount of Weight Loss Six Months after Bariatric Surgery: It Makes a Difference

Olga Nedeljkovic-Arsenovic et al. Obes Facts. 2019.

Abstract

Background: Bariatric surgery, especially Roux-en-Y gastric bypass (RYGB), has become the most frequently used therapy for morbid obesity.

Objectives: The aim of this study was to examine the effects of surgically induced weight loss on cardiopulmonary function 6 months after the procedure, as well as the effect of such an intervention on well-known risk factors for cardiovascular diseases.

Methods: This is a cross-sectional study on 66 morbidly obese patients (BMI ≥40 or ≥35 kg/m2 with present comorbidities), comparing their cardiopulmonary function prior to and 6 months after RYGB surgery.

Results: The substantial amount of weight loss (29.80 ± 13.27 kg) after RYGB surgery was associated with significant reduction of comorbidities, especially diabetes and sedentary lifestyle (p = 0.005 and p = 0.002, respectively). Regarding functional capacity, there was significant increase in peak oxygen uptake (VO2 peak, p = 0.003), duration of exercise testing, metabolic equivalents (exercise time and METs, p < 0.001), and in peak O2 pulse. These findings were particularly pronounced in a group of patients who had lost more than 18% of initial weight.

Conclusions: Reduction of body weight after RYGB surgery is associated with significantly improved cardiorespiratory function 6 months after surgery, especially in patients who lost more than 18% of their initial body weight. In addition, substantial decreases in body weight were also associated with a reduction of cardiovascular risk factors such as diabetes, smoking, hypertriglyceridemia, and sedentary lifestyle.

Keywords: Bariatric surgery; Cardiopulmonary exercise test; Functional capacity; Roux-en-Y gastric bypass.

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Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

Fig. 1
Fig. 1
Flow chart of inclusion and exclusion criteria.
Fig. 2
Fig. 2
Number of antihypertensive drugs before and 6 months after bariatric surgery.
Fig. 3
Fig. 3
Average of peak VO2 in patients with bariatric surgery according to decrease of BM (<18 and >18%) before versus 6 months after bariatric surgery.
See this image and copyright information in PMC

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