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. 2019 Feb 11;4(1):15.
doi: 10.3390/biomimetics4010015.

Synthesis and Characterization of Acetic Acid-Doped Polyaniline and Polyaniline⁻Chitosan Composite

Bianca Rae Pasela  1 , Acelle Pearl Castillo  2 , Rhenish Simon  3 , Maria Teresa Pulido  4 , Haidee Mana-Ay  5 , Ma Roxan Abiquibil  6 , Rhys Montecillo  7 , Kanjana Thumanu  8 , Doebner von Tumacder  9 , Kathrina Lois Taaca  10
Affiliations

Synthesis and Characterization of Acetic Acid-Doped Polyaniline and Polyaniline⁻Chitosan Composite

Bianca Rae Pasela et al. Biomimetics (Basel). .

Abstract

Polyaniline-chitosan (PAni-Cs) composite films were synthesized using a solution casting method with varying PAni concentrations. Polyaniline powders used in the composite synthesis were polymerized using acetic acid as the dopant media. Raman spectroscopy revealed that the PAni powders synthesized using hydrochloric acid and acetic acid did not exhibit significant difference to the chemical features of PAni, implying that PAni was formed in varying concentrations of the dopant media. The presence of agglomerated particles on the surface of the Cs composite, which may have been due to the presence of PAni powders, was observed with scanning electron microscope-energy dispersive X-ray spectroscopy (SEM-EDX). Ultraviolet-visible (UV-Vis) spectroscopy further showed the interaction of PAni with Cs where the Cs characteristic peak shifted to a higher wavelength. Cell viability assay also revealed that the synthesized PAni-Cs composites were nontoxic and may be utilized for future biomedical applications.

Keywords: chitosan; composite; emeraldine; polyaniline; trypan blue assay.

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Conflict of interest statement

The authors declare no conflict of interest in this study.

Figures

Figure 1
Figure 1
Raman spectra of polyaniline (PAni) powders polymerized under constant aniline (An) concentration (5.48 M) and different concentrations of acid dopants: (A) 0.1 M HCl; (B) 0.1 M CH3COOH; (C) 0.01 M HCl; and (D) 0.01 M CH3COOH. a.u.: Arbitrary units.
Figure 2
Figure 2
Scanning electron microscopy (SEM) images of polyaniline–chitosan (PAni–Cs) composite films observed at a magnification of 500×, accelerating voltage of 5 kV, and working distance of 18.1 mm. (a) Pure chitosan (Cs), (b) 1:10 PAni–Cs, and (c) 1:1 PAni–Cs.
Figure 3
Figure 3
Ultraviolet–visible (UV–Vis) spectra of (a) pure chitosan (Cs), (b) 1:10 polyaniline–chitosan (PAni–Cs), and (c) 1:1 PAni–Cs.
Figure 4
Figure 4
Synchrotron radiation-based Fourier-transform infrared (SR-FTIR) spectra of Pure Cs, 1:10 PAni–Cs, and 1:1 PAni-Cs composites. a.u.: Arbitrary units.
Figure 5
Figure 5
Amount of amide present in pure chitosan (Cs), 1:10 polyaniline–chitosan (PAni–Cs), and 1:1 PAni–Cs composites.
Figure 6
Figure 6
Absorbance of the C–H stretching bands present in pure chitosan (Cs), 1:10 polyaniline–chitosan (PAni–Cs), and 1:1 PAni–Cs composites.
Figure 7
Figure 7
Cytocompatibility assay of (a) positive and (b) negative controls, supplemented RPMI and 0.1% Triton X-100, respectively.
Figure 8
Figure 8
Cytocompatibility assay of (a) pure chitosan (Cs), (b) 1:10 polyaniline–chitosan (PAni–Cs), and (c) 1:1 PAni–Cs.
Figure 9
Figure 9
Cell viability of the supplemented RPMI (positive) and Triton X-100 (negative) and the polyaniline–chitosan (PAni–Cs) composite films.
See this image and copyright information in PMC

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