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Review
. 2019 May 3:12:1179547619846088.
doi: 10.1177/1179547619846088. eCollection 2019.

Helicobacter pylori Colonisation in Heterotopic Gastric Mucosa in Meckel Diverticulum: Case Report and Review of the Literature

Thomas Surya Suhardja  1 , Hock Kua  2 , Zoltan Hrabovszky  1
Affiliations
Review

Helicobacter pylori Colonisation in Heterotopic Gastric Mucosa in Meckel Diverticulum: Case Report and Review of the Literature

Thomas Surya Suhardja et al. Clin Med Insights Case Rep. .

Abstract

Meckel diverticulum is the most common congenital abnormality of the gastrointestinal system. Although most Meckel diverticula are asymptomatic, they can also present with bleeding, obstruction, or perforation. Helicobacter pylori is pathognomonic for the development of a peptic ulcer. We present a case report of a patient with a Meckel diverticulum with Helicobacter pylori colonising its heterotopic gastric mucosa. This is a rare histopathologic finding. We also reviewed the literature of other similar cases published in English.

Keywords: Helicobacter pylori; Meckel diverticulum; heterotopic mucosa; laparotomy; peptic ulcer; perforation.

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Conflict of interest statement

Declaration of conflicting interests:The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Intraoperative image of a minilaparotomy showing Meckel diverticulum (arrowhead – Meckel diverticulum; arrow – small intestine).
Figure 2.
Figure 2.
Histopathologic findings: (A) low-power histopathologic view of the small bowel mucosa (right) and gastric mucosa with acid-secreting glands (left) (H&E). (B) Medium-power histopathologic view of the clusters of parietal cells acid-secreting glands with scattered lymphocytes present between the glands (H&E). (C) Immunohistochemical staining with anti-Helicobacter pylori (SP48) Rabbit Monoclonal Primary Antibody (VENTANA anti-H pylori (SP48)) confirmed diagnosis of H pylori infection. H&E indicates haematoxylin and eosin.
See this image and copyright information in PMC

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