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. 2019 Apr 26:10:433.
doi: 10.3389/fneur.2019.00433. eCollection 2019.

Acupuncture for Post-stroke Shoulder-Hand Syndrome: A Systematic Review and Meta-Analysis

Shaonan Liu  1   2   3   4 , Claire Shuiqing Zhang  5 , Yiyi Cai  1   2   3   4   5 , Xinfeng Guo  1   2   3   4 , Anthony Lin Zhang  5 , Charlie Changli Xue  1   3   4   5 , Chuanjian Lu  1   3   4   5
Affiliations

Acupuncture for Post-stroke Shoulder-Hand Syndrome: A Systematic Review and Meta-Analysis

Shaonan Liu et al. Front Neurol. .

Abstract

Background: Shoulder-hand syndrome (SHS) is prevalent in hemiplegic patients after stroke. Potential benefits of acupuncture were shown in recent clinical trials. This systematic review aimed to comprehensively evaluate the safety and efficacy of acupuncture for SHS in stroke patients. Methods: Five English databases (PubMed, Embase, CINAHL, CENTRAL, and AMED) and four Chinese databases (CBM, CNKI, CQVIP, and Wanfang) were searched from their inceptions to January 2019. Randomized, controlled trials that evaluated the add-on effects of acupuncture to rehabilitation for post-stroke SHS were identified. Results: Thirty-eight studies involving 3,184 participants fulfilled the eligible criteria and were included in the review. The overall meta-analysis showed that acupuncture combined with rehabilitation significantly improved motor function (upper-limb Fugl-Meyer Assessment (FMA): 34 studies, mean difference (MD) 8.01, 95% confidence interval (CI) [6.69,9.33]), and reduced pain (visual analog scale (VAS): 25 studies, MD -1.59, 95%CI [-1.86,-1.32]). It also improved activities of daily living (ADL) when compared with rehabilitation alone (ADL: 11 studies, MD 9.99, 95%CI [5.91,14.06]). However, the certainty of evidence of all these outcomes was assessed as "low." Subgroup analyses of acupuncture stimulation types and treatment duration all showed significant add-on effects comparing with rehabilitation alone. The safety of acupuncture was unclear because there is a lack of detailed reporting of adverse events in most of the included studies. Conclusions: Acupuncture therapy seems effective for motor function, pain relief and activities of daily living in stroke patients with mild SHS, when it is used in combination with rehabilitation. The low certainty of evidence downgrades our confidence in making recommendations to clinical practice.

Keywords: acupuncture; rehabilitation; shoulder-hand syndrome; stroke; systematic review.

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Figures

Figure 1
Figure 1
PRISMA flow chart.
Figure 2
Figure 2
Risk of bias of each study.
Figure 3
Figure 3
Forest plot of FMA.
Figure 4
Figure 4
Forest plot of VAS.
See this image and copyright information in PMC

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References

    1. Kocabas H, Levendoglu F, Ozerbil OM, Yuruten B. Complex regional pain syndrome in stroke patients. Int J Rehabil Res. (2007) 30:33–8. 10.1097/MRR.0b013e3280146f57 - DOI - PubMed
    1. Petchkrua W, Weiss DJ, Patel RR. Reassessment of the incidence of complex regional pain syndrome type 1 following stroke. Neurorehabil Neural Repair. (2000) 14:59–63. 10.1177/154596830001400107 - DOI - PubMed
    1. Pertoldi S, Di Benedetto P. Shoulder-hand syndrome after stroke. A complex regional pain syndrome. Eura Medicophys. (2005) 41:283–92. - PubMed
    1. Swati M, Teasull R, Foley N. Evidence-Based Review of Stroke Rehabilitation–Hemiplegic Shoulder Pain. Available online at: www.ebrsr.com (accessed April 10, 2018).
    1. Forouzanfar T, Koke AJ, van Kleef M, Weber WE. Treatment of complex regional pain syndrome type I. Eur J Pain. (2002) 6:105–22. 10.1053/eujp.2001.0304 - DOI - PubMed

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