Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2019 Sep 1;200(5):526-527.
doi: 10.1164/rccm.201904-0899ED.

Deconstructing Hyperlactatemia in Sepsis Using Central Venous Oxygen Saturation and Base Deficit

Affiliations
Comment

Deconstructing Hyperlactatemia in Sepsis Using Central Venous Oxygen Saturation and Base Deficit

Matthew W Semler et al. Am J Respir Crit Care Med. .
No abstract available

PubMed Disclaimer

Comment on

  • Understanding Lactatemia in Human Sepsis. Potential Impact for Early Management.
    Gattinoni L, Vasques F, Camporota L, Meessen J, Romitti F, Pasticci I, Duscio E, Vassalli F, Forni LG, Payen D, Cressoni M, Zanella A, Latini R, Quintel M, Marini JJ. Gattinoni L, et al. Am J Respir Crit Care Med. 2019 Sep 1;200(5):582-589. doi: 10.1164/rccm.201812-2342OC. Am J Respir Crit Care Med. 2019. PMID: 30985210 Clinical Trial.

References

    1. Huckabee WE. Abnormal resting blood lactate: I. The significance of hyperlactatemia in hospitalized patients. Am J Med. 1961;30:840–848. - PubMed
    1. Weil MH, Afifi AA. Experimental and clinical studies on lactate and pyruvate as indicators of the severity of acute circulatory failure (shock) Circulation. 1970;41:989–1001. - PubMed
    1. Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3) JAMA. 2016;315:801–810. - PMC - PubMed
    1. Gattinoni L, Vasques F, Camporota L, Meessen J, Romitti F, Pasticci I, et al. Understanding lactatemia in human sepsis: potential impact for early management Am J Respir Crit Care Med 2019200582–589.. - PubMed
    1. Caironi P, Tognoni G, Masson S, Fumagalli R, Pesenti A, Romero M, et al. ALBIOS Study Investigators. Albumin replacement in patients with severe sepsis or septic shock. N Engl J Med. 2014;370:1412–1421. - PubMed