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Review
. 2019 May 17;24(10):1912.
doi: 10.3390/molecules24101912.

Carbazole Derivatives as Antiviral Agents: An Overview

Anna Caruso  1 , Jessica Ceramella  2 , Domenico Iacopetta  3 , Carmela Saturnino  4 , Maria Vittoria Mauro  5 , Rosalinda Bruno  6 , Stefano Aquaro  7 , Maria Stefania Sinicropi  8
Affiliations
Review

Carbazole Derivatives as Antiviral Agents: An Overview

Anna Caruso et al. Molecules. .

Abstract

Keywords: carbazole; tetrahydrocarbazole; antiviral agents.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Structure of 5-methoxy-7-methyl-7H-pyrido[4,3-c]carbazole (1).
Figure 2
Figure 2
Structures of O-methylmukonal (2), 3-formyl-2,7-dimethoxycarbazole (3) and clauszoline J (4).
Figure 3
Figure 3
Structures of 8-chloro-2-[2-(dimethylamino)ethyl]-9-hydroxy-5-methylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione (5) and derivatives 6–11.
Figure 4
Figure 4
Structures of xiamycin (12), and its methyl ester (13).
Figure 5
Figure 5
Structure of 7-chloro-1,4-dimethyl-3-nitro-9H-carbazole (14).
Figure 6
Figure 6
Structures of 12,13-dihydro-2,10-difluoro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-(6H)-dione (15), Arcyriaflavin A (16), and Go 6976 (17).
Figure 7
Figure 7
Structures of indolocarbazoles K252a (18) and K252c (19).
Figure 8
Figure 8
Structures of 2,3,4,9-tetrahydro-1H-carbazole derivatives 20–22.
Figure 9
Figure 9
Structure of staurosporine (23).
Figure 10
Figure 10
Structure of arylthiourea-carbazole derivative (24).
Figure 11
Figure 11
Structure of 6-cyano-5-methoxy-12-methylindolo [2,3-a]carbazole (25).
Figure 12
Figure 12
Structures of carbazole alkaloids from Glycosmis arborea (26–30).
Figure 13
Figure 13
Structure of N-[(1R)-6-Chloro-2,3,4,9-tetrahydro-1H-carbazol-1-yl]-2-pyridinecarboxamide (GSK983, 31).
Figure 14
Figure 14
General structure of 1-aminotetrahydrocarbazoles (32).
Figure 15
Figure 15
Structures of N-benzyl-6-bromotetrahydrocarbazoleamine (33), N-α-methylbenzyl-6-bromotetrahydrocarbazoleamine (34) and N-dimethylbenzyl-6-bromotetrahydrocarbazoleamine (35).
Figure 16
Figure 16
Structure of (1R)-6-bromo-N-[(1R)-1-phenylethyl]-2,3,4,9-tetrahydro-1H-carbazole-1-amine (36).
Figure 17
Figure 17
Structures of tetrahydrocarbazole amides 37–38.
See this image and copyright information in PMC

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