Treatment of severe obsessive-compulsive disorder with fluvoxamine
- PMID: 3111279
- DOI: 10.1176/ajp.144.8.1059
Treatment of severe obsessive-compulsive disorder with fluvoxamine
Abstract
Ten obsessive-compulsive patients received single-blind treatment with fluvoxamine, a selective serotonin reuptake inhibitor, for several weeks following at least 2 weeks of placebo. The group showed significant improvement, as measured by several clinical scales and self-ratings; six patients were judged responders. Fluvoxamine appears effective in treating severe obsessive-compulsive disorder.
Similar articles
-
Fluvoxamine treatment of obsessive-compulsive disorder.Am J Psychiatry. 1987 Dec;144(12):1543-8. doi: 10.1176/ajp.144.12.1543. Am J Psychiatry. 1987. PMID: 3120604 Clinical Trial.
-
Efficacy of fluvoxamine in obsessive-compulsive disorder. A double-blind comparison with placebo.Arch Gen Psychiatry. 1989 Jan;46(1):36-44. doi: 10.1001/archpsyc.1989.01810010038006. Arch Gen Psychiatry. 1989. PMID: 2491940 Clinical Trial.
-
A controlled trial of fluvoxamine in obsessive-compulsive disorder: implications for a serotonergic theory.Am J Psychiatry. 1990 Sep;147(9):1209-15. doi: 10.1176/ajp.147.9.1209. Am J Psychiatry. 1990. PMID: 2143637 Clinical Trial.
-
Fluvoxamine as an antiobsessional agent.Psychopharmacol Bull. 1989;25(1):31-5. Psychopharmacol Bull. 1989. PMID: 2505302 Review.
-
Controlled-release fluvoxamine in obsessive-compulsive disorder and social phobia.Drugs Today (Barc). 2008 Dec;44(12):887-93. doi: 10.1358/dot.2008.44.12.1299291. Drugs Today (Barc). 2008. PMID: 19198698 Review.
Cited by
-
A risk-benefit assessment of drugs used in the management of obsessive-compulsive disorder.Drug Saf. 1996 Aug;15(2):116-34. doi: 10.2165/00002018-199615020-00004. Drug Saf. 1996. PMID: 8884163 Review.
-
Electrocardiographic alterations as a result of acute intoxication with fluvoxamine and pipamperone.Clin Drug Investig. 1998;15(1):64-8. doi: 10.2165/00044011-199815010-00009. Clin Drug Investig. 1998. PMID: 18370468 No abstract available.
-
Treatment of obsessive-compulsive disorder in children and adolescents. A review of the literature.Eur Child Adolesc Psychiatry. 1996 Jun;5(2):55-66. doi: 10.1007/BF01989497. Eur Child Adolesc Psychiatry. 1996. PMID: 8814411 Review.
-
Neurochemical responses to antidepressants in the prefrontal cortex of mice and their efficacy in preclinical models of anxiety-like and depression-like behavior: a comparative and correlational study.Psychopharmacology (Berl). 2008 May;197(4):567-80. doi: 10.1007/s00213-008-1070-6. Epub 2008 Feb 15. Psychopharmacology (Berl). 2008. PMID: 18274731
-
Initial orthostatic hypotension as a cause of recurrent syncope: a case report.Clin Auton Res. 2001 Aug;11(4):269-70. doi: 10.1007/BF02298960. Clin Auton Res. 2001. PMID: 11710801
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Medical