Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1978 Dec 15;209(2):73-82.
doi: 10.1007/BF00407840.

Experimental corticosteroid ocular hypertension in the rabbit

L Bonomi, S Perfetti, E Noya, R Bellucci, L Tomazzoli

Experimental corticosteroid ocular hypertension in the rabbit

L Bonomi et al. Albrecht Von Graefes Arch Klin Exp Ophthalmol. .

Abstract

Weekly subconjunctival injections of 4mg repository betamethasone, repeated over three weeks, produced a sustained increase of intraocular pressure (IOP) in 96% of the treated rabbits. Treatment was generally well tolerated and important systemic toxic effects were present only in a few animals. The ocular hypertension so obtained was constant, well reproducible and sensitive to antiglaucoma drugs. The authors believe they have developed an animal model which is very suitable for testing the pressure-lowering effect of drugs and for other studies on ocular hypertension and glaucoma.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Klin Oczna. 1969;39(4):549-53 - PubMed
    1. Invest Ophthalmol Vis Sci. 1977 Jul;16(7):592-6 - PubMed
    1. Klin Monbl Augenheilkd. 1963 Jul;142:982-1006 - PubMed
    1. Am J Ophthalmol. 1974 Sep;78(3):505-10 - PubMed
    1. Arch Ophthalmol. 1969 Aug;82(2):259-63 - PubMed