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Comment
. 2019 Jun;4(6):912-913.
doi: 10.1038/s41564-019-0473-y.

Microbiome genome structure drives function

Matthew G Durrant  1 , Ami S Bhatt  2   3
Affiliations
Comment

Microbiome genome structure drives function

Matthew G Durrant et al. Nat Microbiol. 2019 Jun.

Abstract

Differences in microbial genomes can result in vastly different phenotypes and functions. Consequently, it is critical to understand the genome variations that differentiate microbial strains. Here, we discuss recent exciting advances that enable structural variant measurement, their associated phenotypes and the horizon for future discovery.

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Conflict of interest statement

Competing interests

The authors declare no competing interests.

Figures

Fig. 1 |
Fig. 1 |. Structural variation in the gut microbiome.
Structural variations at the level of individual microbial genomes in the human gut microbiome associate with metabolic phenotypes in the human host, including body weight, cholesterol and other markers of metabolic disease risk.
See this image and copyright information in PMC

Comment on

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