[Pharmacokinetics of antineoplastic agents (author's transl)]
[Article in
French]
- PMID: 311229
Item in Clipboard
[Pharmacokinetics of antineoplastic agents (author's transl)]
[Article in
French]
Bull Cancer.
1979.
Abstract
The general basis of pharmacokinetics are summarized with the clinical aims of a better utilisation of drugs by the application pharmacokinetic data. The subject is illustrated by some antineoplastic agents especially on high dose methotrexate regimens and clinical use of 5 FU. A pharmacokinetic model may be described with the first agent but for 5 FU no specific model has yet been demonstrated. Some examples of studies on adriamycin and cytosine arabinoside are then given.
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