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. 2019 Apr 15;6(5):ofz190.
doi: 10.1093/ofid/ofz190. eCollection 2019 May.

Invasive Meningococcal Disease due to Nongroupable Neisseria meningitidis-Active Bacterial Core Surveillance Sites, 2011-2016

Lucy A McNamara  1 , Caelin C Potts  1 , Amy Blain  1 , Nadav Topaz  1 , Mirasol Apostol  2 , Nisha B Alden  3 , Susan Petit  4 , Monica M Farley  5 , Lee H Harrison  6 , Lori Triden  7 , Alison Muse  8 , Tasha Poissant  9 , Xin Wang  1 , Jessica R MacNeil  10
Affiliations

Invasive Meningococcal Disease due to Nongroupable Neisseria meningitidis-Active Bacterial Core Surveillance Sites, 2011-2016

Lucy A McNamara et al. Open Forum Infect Dis. .

Abstract

We characterized 22 meningococcal disease cases due to nongroupable Neisseria meningitidis, a rare cause of invasive disease. Disease presentation and severity were similar to those for serogroupable meningococcal disease. However, 7 (32%) patients had complement deficiency or abnormal complement testing results, highlighting the importance of complement testing for nongroupable cases.

Keywords: Neisseria meningitidis; complement component deficiency; meningococcal disease; nongroupable.

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