Are women with cervical incompetence at a higher risk of experiencing urinary and pelvic organ prolapse symptoms?

Abstract

Introduction and hypothesis: Pelvic organ prolapse (POP) and lower urinary tract symptoms (LUTs), in addition to cervical incompetence, have a multifactorial etiology. Connective tissue disorders are common risk factors in both entities. The objective of this study was to compare long-term urinary and pelvic organ prolapse-related symptoms in patients who experienced cervical incompetence and those who did not.

Methods: In this historical prospective cohort, analysis of cervical incompetence cases from one medical center between 2006 and 2009 were compared with a matched control group. All cases included a minimum 7-year follow-up. Symptoms of urinary and prolapse-related complaints during follow-up were evaluated based on the Pelvic Floor Distress Inventory-20 questionnaire.

Results: The study group comprised 37 women who experienced cervical incompetence matched to 34 consecutive controls. There was no difference between the groups in demographic or obstetric characteristics, except for a higher cesarean section rate and earlier deliveries among women with cervical incompetence. On assessment of patient's symptoms, during follow-up, the average Pelvic Organ Prolapse Distress Inventory-6 score was significantly higher in patients who experienced cervical incompetence than in controls (15.0 ± 26.1 vs 1.7 ± 7.1 respectively, p = 0.034). Urinary complaints, as reflected by the Urinary Distress Inventory-6 index, were also more common in women with cervical incompetence (17.9 ± 19.1 vs 3.9 ± 7.3 p = 0.027).

Conclusions: Women with a history of cervical incompetence experienced a higher rate of pelvic organ prolapse and urinary symptoms compared with women who had no cervical insufficiency.

Keywords: Cervical incompetence; Overactive bladder; Pelvic organ prolapse; Urinary incontinence.