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. 1978 Dec;34(3):374-8.

Suppression of B lymphocyte differentiation by newborn T lymphocytes with an Fc receptor for IgM

A R Hayward, P M Lydyard

Suppression of B lymphocyte differentiation by newborn T lymphocytes with an Fc receptor for IgM

A R Hayward et al. Clin Exp Immunol. 1978 Dec.

Abstract

The IgM (Fc)-binding subpopulation of human newborn T lymphocytes (TM) suppressed the pokeweed mitogen induced differentiation of adult B lymphocytes. Positively isolated IgG (Fc)-binding T lymphocytes (TG) also suppressed, but lymphocyte preparations negatively enriched for TG by the depletion of TM cells were not suppressive. The Fc receptor specificity of the human newborn suppressor appears to resemble that of the human Con A suppressor.

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References

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