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Review
. 2019 Nov;106(11):1023-1028.
doi: 10.1016/j.bulcan.2019.04.003. Epub 2019 May 22.

[HIPEC in ovarian cancer: What should we expect?]

[Article in French]
Léonie Picard  1 , Charlotte Bourgin  2 , Frédérique Penault-Llorca  1 , Marie Beguinot  1 , Caroline Cornou  1 , Guillaume Le Bouedec  1 , Marie-Ange Mouret-Reynier  1 , Frédéric Selle  3 , Christophe Pomel  4
Affiliations
Review

[HIPEC in ovarian cancer: What should we expect?]

[Article in French]
Léonie Picard et al. Bull Cancer. 2019 Nov.

Abstract

The results of PRODIGE 7 study demonstrate that the use of HIPEC is not beneficial for patients in the treatment of colorectal carcinomatosis. Nevertheless, a recent study published in NewEnglandJournalofMedicine showed that hyperthermic intraperitoneal chemotherapy (HIPEC) increased overall survival for patients with ovarian peritoneal carcinomatosis. Although, the emergence of targeted therapies (anti-angiogenic agents, PARP-inhibitors, anti-PDL1) results in new standards of treatment in first line or recurrence disease. In this general context, what is the potential interest of HIPEC for the treatment of ovarian carcinoma?

Keywords: CHIP; Carcinomatosis; Carcinose; HIPEC; Ovaire; Ovarian.

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