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Comment
. 2019 Jul;9(7):OF1.
doi: 10.1158/2159-8290.CD-NB2019-061. Epub 2019 May 24.

High ORRs Seen with Tagraxofusp-erzs in BPDCN

No authors listed
Comment

High ORRs Seen with Tagraxofusp-erzs in BPDCN

No authors listed. Cancer Discov. 2019 Jul.

Abstract

Tagraxofusp-erzs is an effective therapy for blastic plasmacytoid dendritic-cell neoplasm, according to recently published results from a multistage trial that led to the drug's 2018 approval. In the trial, the drug elicited high overall response rates, and many patients went on to receive a stem-cell transplant. However, it also caused some serious side effects.

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Comment on

  • Tagraxofusp in Blastic Plasmacytoid Dendritic-Cell Neoplasm.
    Pemmaraju N, Lane AA, Sweet KL, Stein AS, Vasu S, Blum W, Rizzieri DA, Wang ES, Duvic M, Sloan JM, Spence S, Shemesh S, Brooks CL, Balser J, Bergstein I, Lancet JE, Kantarjian HM, Konopleva M. Pemmaraju N, et al. N Engl J Med. 2019 Apr 25;380(17):1628-1637. doi: 10.1056/NEJMoa1815105. N Engl J Med. 2019. PMID: 31018069 Clinical Trial.