Severe acute ocular hypertension following pulsed methylprednisolone for juvenile idiopathic arthritis
- PMID: 31129643
- PMCID: PMC6536218
- DOI: 10.1136/bcr-2019-229803
Severe acute ocular hypertension following pulsed methylprednisolone for juvenile idiopathic arthritis
Corrected and republished in
-
Republished: Severe acute ocular hypertension following pulsed methylprednisolone for juvenile idiopathic arthritis.Drug Ther Bull. 2019 Oct;57(10):158-159. doi: 10.1136/dtb.2019.229803rep. Epub 2019 Aug 23. Drug Ther Bull. 2019. PMID: 31444222 Free PMC article. No abstract available.
Abstract
We report the case of a 6-year-old girl with juvenile idiopathic arthritis and anterior uveitis who was treated with two doses of intravenous methylprednisolone for acute arthritis. She developed severe ocular hypertension (intraocular pressures (IOPs) of 54 mm Hg in the right eye and 61 mm Hg in the left eye) requiring inpatient therapy with intravenous acetazolamide. The normal range of values for IOP is 12-22 mm Hg. This severe case of acute intraocular hypertension due to systemic steroids highlights the need to consider monitoring of IOPs for children on high-dose topical and systemic steroids with risk factors for raised IOP.
Keywords: glaucoma; paediatrics; paediatrics (drugs and medicines); rheumatology.
© BMJ Publishing Group Limited 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Conflict of interest statement
Competing interests: None declared.
Similar articles
-
Tocilizumab in refractory juvenile idiopathic arthritis with associated uveitis: a case report.Acta Reumatol Port. 2019 Apr-Jun;44(2):151-154. Acta Reumatol Port. 2019. PMID: 31455751 English.
-
Risk of Hypotony in Juvenile Idiopathic Arthritis-Associated Uveitis.Am J Ophthalmol. 2016 Sep;169:113-124. doi: 10.1016/j.ajo.2016.06.026. Epub 2016 Jun 23. Am J Ophthalmol. 2016. PMID: 27345732
-
Therapeutic experience with infliximab in a patient with polyarticular juvenile idiopathic arthritis and uveitis.Rheumatol Int. 2003 Sep;23(5):258-61. doi: 10.1007/s00296-003-0308-1. Epub 2003 Apr 10. Rheumatol Int. 2003. PMID: 12687288
-
Juvenile arthritis and uveitis.Surv Ophthalmol. 1990 Jan-Feb;34(4):253-67. doi: 10.1016/0039-6257(90)90026-r. Surv Ophthalmol. 1990. PMID: 2188388 Review.
-
Immunosuppressive drugs in the management of progressive, corticosteroid-resistant uveitis associated with juvenile rheumatoid arthritis.Int Ophthalmol Clin. 1992 Winter;32(1):241-52. doi: 10.1097/00004397-199203210-00018. Int Ophthalmol Clin. 1992. PMID: 1537661 Review. No abstract available.
Cited by
-
Research progress in drug therapy of juvenile idiopathic arthritis.World J Pediatr. 2022 Jun;18(6):383-397. doi: 10.1007/s12519-022-00530-8. Epub 2022 Apr 1. World J Pediatr. 2022. PMID: 35364799 Review.
References
-
- Chy L, Dorothy SP, Jonathan CH. Corticosteroid-induced glaucoma in children. Hong Kong Journal of Ophthalmology 2014;18:14–19.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical