Aspect en microscopie confocale par réflectance in vivo des kératoses actiniques: Reflectance confocal microscopy features of actinic keratoses

Abstract

Though the diagnosis of actinic keratoses is most often clinical, it is sometimes necessary to use non-invasive imaging methods to confirm this diagnosis. Reflectance confocal microscopic examination of actinic keratosis may reveal hyperkeratosis (i.e., detached, isolated or scaly corneocytes), parakeratosis (i.e., nucleated cells in the stratum corneum), dilated vessels and signs of solar elastosis, including clusters of moderately reflecting material and/or undulating shiny elastic fibres that are clearly visible in the superficial dermis. Hopefully, new in vivo microscopic imaging techniques such as line-field confocal optical coherence tomography will make it possible to obtain a three-dimensional examination of the skin and, thus, to further improve diagnostic accuracy of these lesions. © 2019 Elsevier Masson SAS. All rights reserved. Cet article fait partie du numéro supplément Kératoses actiniques : comprendre et traiter réalisé avec le soutien institutionnel de Galderma International.

Keywords: Actinic keratosis; Dermatoscopie; Dermoscopy; Imagerie non invasive; In vivo confocal microscopy; In vivo reflectance confocal microscopy; Kératose actinique; Line-field confocal optical coherence tomography; Microscopie confocale in vivo; Microscopie confocale par réflectance in vivo; Noninvasive imaging; Optical Coherence Tomography; Tomographie par cohérence optique; Tomographie par cohérence optique confocale à balayage en ligne.