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. 2019 May 9:10:425.
doi: 10.3389/fneur.2019.00425. eCollection 2019.

10Kin1day: A Bottom-Up Neuroimaging Initiative

Martijn P van den Heuvel  1   2 , Lianne H Scholtens  1   2 , Hannelore K van der Burgh  3 , Federica Agosta  4 , Clara Alloza  5   6 , Celso Arango  6 , Bonnie Auyeung  7 , Simon Baron-Cohen  7 , Silvia Basaia  4 , Manon J N L Benders  8 , Frauke Beyer  9 , Linda Booij  10 , Kees P J Braun  11 , Geraldo Busatto Filho  12 , Wiepke Cahn  2 , Dara M Cannon  13 , Tiffany M Chaim-Avancini  12 , Sandra S M Chan  14 , Eric Y H Chen  15 , Benedicto Crespo-Facorro  16 , Eveline A Crone  17 , Udo Dannlowski  18 , Sonja M C de Zwarte  2 , Bruno Dietsche  19 , Gary Donohoe  20 , Stefan Du Plessis  21 , Sarah Durston  2 , Covadonga M Díaz-Caneja  6 , Ana M Díaz-Zuluaga  22 , Robin Emsley  21 , Massimo Filippi  4 , Thomas Frodl  23 , Martin Gorges  24 , Beata Graff  25 , Dominik Grotegerd  18 , Dariusz Gąsecki  26 , Julie M Hall  27 , Laurena Holleran  20 , Rosemary Holt  7 , Helene J Hopman  28 , Andreas Jansen  29 , Joost Janssen  6 , Krzysztof Jodzio  30 , Lutz Jäncke  31 , Vasiliy G Kaleda  32 , Jan Kassubek  24 , Shahrzad Kharabian Masouleh  33 , Tilo Kircher  29 , Martijn G J C Koevoets  2 , Vladimir S Kostic  34 , Axel Krug  29 , Stephen M Lawrie  5 , Irina S Lebedeva  35 , Edwin H M Lee  15 , Tristram A Lett  36 , Simon J G Lewis  27 , Franziskus Liem  37 , Michael V Lombardo  7 , Carlos Lopez-Jaramillo  38 , Daniel S Margulies  39 , Sebastian Markett  40 , Paulo Marques  41 , Ignacio Martínez-Zalacaín  42 , Colm McDonald  13 , Andrew M McIntosh  5 , Genevieve McPhilemy  13 , Susanne L Meinert  18 , José M Menchón  42 , Christian Montag  43 , Pedro S Moreira  41 , Pedro Morgado  41 , David O Mothersill  20 , Susan Mérillat  37 , Hans-Peter Müller  24 , Leila Nabulsi  13 , Pablo Najt  13 , Krzysztof Narkiewicz  25 , Patrycja Naumczyk  30 , Bob Oranje  2 , Victor Ortiz-Garcia de la Foz  44 , Jiska S Peper  17 , Julian A Pineda  45 , Paul E Rasser  46 , Ronny Redlich  18 , Jonathan Repple  18 , Martin Reuter  40 , Pedro G P Rosa  12 , Amber N V Ruigrok  7 , Agnieszka Sabisz  47 , Ulrich Schall  46 , Soraya Seedat  21 , Mauricio H Serpa  48 , Stavros Skouras  49 , Carles Soriano-Mas  50 , Nuno Sousa  41 , Edyta Szurowska  47 , Alexander S Tomyshev  35 , Diana Tordesillas-Gutierrez  51 , Sofie L Valk  52 , Leonard H van den Berg  3 , Theo G M van Erp  53 , Neeltje E M van Haren  2   54 , Judith M C van Leeuwen  55 , Arno Villringer  56 , Christiaan H Vinkers  57 , Christian Vollmar  58 , Lea Waller  59 , Henrik Walter  60 , Heather C Whalley  5 , Marta Witkowska  30 , A Veronica Witte  9 , Marcus V Zanetti  61   62 , Rui Zhang  63 , Siemon C de Lange  1   2
Affiliations

10Kin1day: A Bottom-Up Neuroimaging Initiative

Martijn P van den Heuvel et al. Front Neurol. .

Abstract

We organized 10Kin1day, a pop-up scientific event with the goal to bring together neuroimaging groups from around the world to jointly analyze 10,000+ existing MRI connectivity datasets during a 3-day workshop. In this report, we describe the motivation and principles of 10Kin1day, together with a public release of 8,000+ MRI connectome maps of the human brain.

Keywords: MRI; brain; connectome analysis; diffusion weighted MRI; network.

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Figures

Figure 1
Figure 1
(A) For each dataset, DWI tractography was combined with T1-based parcellation of cerebral brain regions to reconstruct a brain network. (B) Group-averaged (group threshold 33%) FA matrix of the 10K dataset. (C) High overlap (r = 0.93) between group-averaged FA values as derived from high-resolution HCP data and the 10K dataset. (D) Relationship between age and average inverse mean diffusivity (MD, sec/mm2) across the 10K dataset. Colors indicate the different included datasets. Insert shows a pie diagram of the size of included datasets, color coded to set participation. One dataset (set_634413) was excluded from this plot, showing (across the age span) deviating FA (lower) and MD (higher) values than the other datasets (see methods). Due to the high total n, excluding this dataset did not change the relationship with age. (E) Relationship between age and average cortical thickness (CT). (F) Age distribution of the presented data as in (D,E). T1, anatomical MRI; DWI, diffusion weighted imaging; CT, cortical thickness.
See this image and copyright information in PMC

References

    1. Amunts K, Ebell C, Muller J, Telefont M, Knoll A, Lippert T. The Human Brain Project: Creating a European Research Infrastructure to Decode the Human Brain. Neuron. (2016) 92:574–81. 10.1016/j.neuron.2016.10.046 - DOI - PubMed
    1. Insel TR, Landis SC, Collins FS. Research priorities. NIH BRAIN Init Sci.(2013) 340:687–8. 10.1126/science.1239276 - DOI - PMC - PubMed
    1. Van Essen DC, Smith SM, Barch DM, Behrens TE, Yacoub E, Ugurbil K. The WU-Minn Human Connectome Project: an overview. Neuroimage. (2013) 80:62–79. 10.1016/j.neuroimage.2013.05.041 - DOI - PMC - PubMed
    1. Jiang T. Brainnetome: a new -ome to understand the brain and its disorders. Neuroimage. (2013) 80:263–72. 10.1016/j.neuroimage.2013.04.002 - DOI - PubMed
    1. Thompson PM, Andreassen OA, Arias-Vasquez A, Bearden CE, Boedhoe PS, Brouwer RM, et al. . ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide. Neuroimage. (2017) 145:389–408. 10.1016/j.neuroimage.2015.11.057 - DOI - PMC - PubMed