Incidence, Implications, and Management of Seizures Following Ischemic and Hemorrhagic Stroke
- PMID: 31134438
- PMCID: PMC6746168
- DOI: 10.1007/s11910-019-0957-4
Incidence, Implications, and Management of Seizures Following Ischemic and Hemorrhagic Stroke
Abstract
Purpose of review: In this review, we summarize the recent literature regarding the incidence and treatment of seizures arising after ischemic and hemorrhagic strokes. Additionally, we identify open questions in guidelines and standard clinical care to aid future studies aiming to improve management of seizures in post-stroke patients.
Recent findings: Studies demonstrate an increasing prevalence of seizures following strokes, probably a consequence of advances in post-stroke management and expanding use of continuous EEG monitoring. Post-stroke seizures are associated with longer hospitalization and increased mortality; therefore, prevention and timely treatment of seizures are important. The standard of care is to treat recurrent seizures with anti-epileptic drugs (AEDs) regardless of the etiology. However, there are no established guidelines currently for prophylactic use of AEDs following a stroke. The prevalence of post-stroke seizures is increasing. Further studies are needed to determine the risk factors for recurrent seizures and epilepsy after strokes and optimal treatment strategies.
Keywords: Cerebrovascular disease; Epilepsy; Hemorrhagic stroke; Ischemic stroke; Post-stroke seizures; Seizures.
Comment in
-
Modern Antiepileptic Drugs Reduce Seizures and Improve Outcomes in Cortical ICH.Ann Emerg Med. 2020 Oct;76(4):549. doi: 10.1016/j.annemergmed.2020.05.008. Ann Emerg Med. 2020. PMID: 33012383 No abstract available.
-
In reply.Ann Emerg Med. 2020 Oct;76(4):550. doi: 10.1016/j.annemergmed.2020.05.003. Ann Emerg Med. 2020. PMID: 33012384 No abstract available.
References
-
- Sander JW. The epidemiology of epilepsy revisited. Curr Opin Neurol. 2003;16:165–70. - PubMed
-
- Hauser WA, Beghi E. First seizure definitions and worldwide incidence and mortality. Epilepsia. 2008;49 Suppl 1:8–12. - PubMed
-
- Feyissa AM, Hasan TF, Meschia JF. Stroke-related epilepsy. Eur J Neurol. 2019;26:18–e3. - PubMed
-
••A recent paper which discusses epidemiology, risk factors, presentations, mechanisms and management of stroke related epilepsy.
-
- Hasan TF, Rabinstein AA, Middlebrooks EH, Haranhalli N, Silliman SL, Meschia JF, et al. Diagnosis and Management of Acute Ischemic Stroke. Mayo Clin Proc. 2018;93:523–38. - PubMed
-
- Krueger H, Koot J, Hall RE, O’Callaghan C, Bayley M, Corbett D. Prevalence of Individuals Experiencing the Effects of Stroke in Canada: Trends and Projections. Stroke. 2015;46:2226–31. - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Research Materials
