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Observational Study
. 2020 Jul;40(7):1262-1271.
doi: 10.1097/IAE.0000000000002569.

EN FACE IMAGE-BASED ANALYSIS OF RETINAL TRACTION CAUSED BY EPIRETINAL MEMBRANE AND ITS RELATIONSHIP WITH VISUAL FUNCTIONS

Masayuki Hirano  1 , Yuki Morizane  1 , Yuki Kanzaki  1 , Shuhei Kimura  1 , Mio Hosokawa  1 , Yusuke Shiode  1 , Shinichiro Doi  1 , Shinji Toshima  1 , Kosuke Takahashi  1 , Mika Hosogi  1 , Atsushi Fujiwara  1 , Ippei Takasu  2 , Fumio Shiraga  1
Affiliations
Observational Study

EN FACE IMAGE-BASED ANALYSIS OF RETINAL TRACTION CAUSED BY EPIRETINAL MEMBRANE AND ITS RELATIONSHIP WITH VISUAL FUNCTIONS

Masayuki Hirano et al. Retina. 2020 Jul.

Abstract

Purpose: To evaluate the relationship between retinal traction caused by epiretinal membrane and visual functions.

Methods: In this institutional study, en face swept-source optical coherence tomography images of 141 eyes of 130 patients with epiretinal membrane were analyzed to investigate maximum depth of retinal folds, which represents retinal traction strength and the distribution pattern of retinal folds. We investigated the relationships between the maximum depth and distribution pattern of retinal folds and visual functions as well as the effects of membrane peeling.

Results: Maximum retinal fold depth was significantly correlated with the metamorphopsia score (P < 0.001). Fifteen eyes showed retinal folds radially extending from the macular epiretinal membrane (radiating folds group), whereas 126 eyes showed a multidirectional pattern of retinal folds (multidirectional folds group). The radiating folds group showed a significantly lower metamorphopsia score (P = 0.014). Multiple regression analysis revealed that the metamorphopsia score was significantly related to maximum retinal fold depth (P = 0.003), distribution pattern (P = 0.015), and central retinal thickness (P < 0.001). One month after membrane peeling, parafoveal retinal folds resolved completely in all cases, and both visual acuity (P < 0.001) and average metamorphopsia score (P = 0.036) were significantly improved.

Conclusion: Both the strength and the distribution pattern of retinal traction are significantly related to metamorphopsia in epiretinal membrane patients.

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