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Review
. 2019 May 20;20(10):2479.
doi: 10.3390/ijms20102479.

Jasmonic Acid Signaling Pathway in Plants

Jingjun Ruan  1   2 , Yuexia Zhou  3 , Meiliang Zhou  4 , Jun Yan  5 , Muhammad Khurshid  6   7 , Wenfeng Weng  8 , Jianping Cheng  9 , Kaixuan Zhang  10
Affiliations
Review

Jasmonic Acid Signaling Pathway in Plants

Jingjun Ruan et al. Int J Mol Sci. .

Abstract

Jasmonic acid (JA) and its precursors and dervatives, referred as jasmonates (JAs) are important molecules in the regulation of many physiological processes in plant growth and development, and especially the mediation of plant responses to biotic and abiotic stresses. JAs biosynthesis, perception, transport, signal transduction and action have been extensively investigated. In this review, we will discuss the initiation of JA signaling with a focus on environmental signal perception and transduction, JA biosynthesis and metabolism, transport of signaling molecules (local transmission, vascular bundle transmission, and airborne transportation), and biological function (JA signal receptors, regulated transcription factors, and biological processes involved).

Keywords: biological function; environmental response; jasmonic acid; signaling pathway.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Scheme of the JAs biosynthesis pathway in Arabidopsis thaliana. The enzymes and the intermediates are indicated as follows: LOX for lipoxygenase, AOS for allene oxide synthase, AOC for allene oxide cyclase, OPR3 for OPDA reductase, JAR1 for jasmonate resistant 1, JMT for JA carboxyl methyltransferase; 18:3 for α-linolenic acid, 16:3 for hexadecatrienoic acid, OPDA for 12-oxo-phytodienoic acid, dnOPDA for dinor-12-oxo-phytodienoic acid, OPC8 for 8-(3-oxo-2-(pent-2-enyl)cyclopentyl) octanoic acid, OPC6 for 6-(3-oxo-2-(pent-2-enyl)cyclopentyl) hexanoic acid, OPC4 for 4-(3-oxo-2-(pent-2-enyl)cyclopentyl) butanoic acid, tnOPDA for tetranor-OPDA, 4,5-ddh-JA for 4,5-didehydrjasmonate, JA for jasmonic acid, JA-Ile for jasmonoyl-L-isoleucine, and MeJA for methyl jasmonate.
Figure 2
Figure 2
The working model of jasmonic acid transport and signaling pathway. JAT1: jasmonic acid transfer protein1; SCF: Skp1, Cullin and F-box proteins; COI1: coronatine insensitive1; JAZ: jasmonate ZIM-domain protein; TF: transcription factor; TPL: TOPLESS protein; NINJA: NOVEL INTERACTOR OF JAZ; 26S: 26S proteasome.
Figure 3
Figure 3
The regulation network of the jasmonic acid signaling pathway. Biotic and abiotic stresses induce the synthesis of JA, which can be converted to the biologically active JA-Ile by JAR1. Perception of JA-Ile by its receptor COI1 triggers the degradation of JAZ repressors, leading to the release of downstream transcription factors and the regulation of JAs-responsive genes in various processes. The question marker indicates an adaptor protein which is not identified yet.
See this image and copyright information in PMC

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