Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 May;32(5):616-622.
doi: 10.1080/09540121.2019.1622630. Epub 2019 May 28.

Lessons learned from a mobile technology-based intervention informed by behavioral economics to improve ART adherence among youth in Uganda

Affiliations

Lessons learned from a mobile technology-based intervention informed by behavioral economics to improve ART adherence among youth in Uganda

Sarah MacCarthy et al. AIDS Care. 2020 May.

Abstract

Evidence suggests that simple text messaging interventions may not suffice to improve ART adherence among youth in low-resource settings. To address this shortcoming, we developed an intervention that shared weekly real-time adherence feedback to youth in Uganda using short message services (SMS), based on information tracked by an electronic device (Wisepill). We present results from 7 formative and 6 exit focus groups (FGs) in Mulago and Entebbe, Uganda with youth ages 15-24, providers, and Community Advisory Board members. Participants consistently conveyed positive impressions of Wisepill, noting that it helped store their medications, facilitated travel, served as a reminder, and motivated adherence. Participants raised phone-related issues before the study; most were addressed but some remained (e.g., limited network access, electricity for powering phones). Further, they highlighted the importance of carefully crafting text messages (e.g., use slang rather than potentially stigmatizing words) and viewed personalizing messages favorably but were divided on the desirability of including their name in study-related texts. Exit FGs confirmed that sharing group adherence levels with participants tapped into the competitive spirit common among youth. Our results suggest future mobile technology-based interventions can be improved by providing messages that go beyond simple reminders to provide individual and group-level adherence feedback.

Keywords: HIV; Mobile technology; behavioral economics; text message.

PubMed Disclaimer

Conflict of interest statement

CONFLICT OF INTEREST

None of the authors have potential, perceived, or real conflict of interest. The sponsor (NIH) had no involvement in the: 1) study design; 2) collection, analysis and interpretation of data; 3) the writing of the report; and (4) the decision to submit the manuscript for publication. SM wrote the first draft of the manuscript and no honorarium, grant, or other form of payment was given to anyone to produce the manuscript.

Disclosure of potential conflicts, real and perceived, for all named authors: N/A

References

    1. Bachman DeSilva M, Gifford AL, Keyi X, Li Z, Feng C, Brooks M, Wubin X (2013). Feasibility and acceptability of a real-time adherence device among HIV-positive IDU patients in China. AIDS Res Treat, 2013 - PMC - PubMed
    1. Bigna JJR, Noubiap JJN, Kouanfack C, Plottel CS, & Koulla-Shiro S (2014). Effect of mobile phone reminders on follow-up medical care of children exposed to or infected with HIV in Cameroon (MORE CARE): a multicentre, single-blind, factorial, randomised controlled trial. The Lancet Infectious Diseases, 14(7), pp. 600–608. - PubMed
    1. Bikaako-Kajura W, Luyirika E, Purcell DW, Downing J, Kaharuza F, Mermin J, Bunnell R (2006). Disclosure of HIV status and adherence to daily drug regimens among HIV-infected children in Uganda. AIDS and Behavior, 10, pp. S85–S93. doi:10.1007/s10461-006-9141-3 Retrieved from <Go to ISI>://WOS:000239592400010 - DOI - PubMed
    1. Bionghi N, Daftary A, Maharaj B, Msibi Z, Amico K, Friedland G, O’Donnell M (2018). Pilot evaluation of a second-generation electronic pill box for adherence to Bedaquiline and antiretroviral therapy in drug-resistant TB/HIV co-infected patients in KwaZulu-Natal, South Africa. BMC Infect Dis, 18(1), p 171. - PMC - PubMed
    1. Blashill AJ, Safren SA, Wilhelm S, Jampel J, Taylor SW, O’Cleirigh C, & Mayer KH (2017). Cognitive behavioral therapy for body image and self-care (CBT-BISC) in sexual minority men living with HIV: A randomized controlled trial. Health Psychol, 36(10), p 937. - PMC - PubMed

Publication types