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Published Erratum
. 2019 Jun 4;116(23):11553-11554.
doi: 10.1073/pnas.1907473116. Epub 2019 May 28.

Correction for Kröger et al., Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells

No authors listed
Published Erratum

Correction for Kröger et al., Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells

No authors listed. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

Fig. 3.
Fig. 3.
Zeb1 is needed for a complete EMT, but the hybrid E/M cell state is sufficient for tumor formation. (A) Representative images of cell morphology of E-SCC, E-SCCSn, E-SCC-Zeb1KO, and E-SCC-Zeb1KOSn cells by phase contrast (brightfield) microscopy. (B) FACS profiles for CD104 and CD44 of E-SCC, E-SCCSn, E-SCC-Zeb1KO, and E-SCC-Zeb1KOSn populations. (C) Assessment of tumorigenicity and tumor growth by tumor weight of orthotopic injection E-SCC, E-SCCSn, E-SCC-Zeb1KO, and E-SCC-Zeb1KOSn populations. Data are presented as mean ± SEM (D) Differences in tumor-initiating ability of E-SCC, E-SCCSn, E-SCC-Zeb1KO, and E-SCC-Zeb1KOSn cells upon transplantation at limiting dilutions into NOD/SCID mice. (E) Analysis of E-SCC, E-SCCSn, E-SCC-Zeb1KO, and E-SCC-Zeb1KOSn tumor sections using H&E and IF staining for Krt/Zeb1 or Snail. LgT staining was used to differentiate tumor cells from mouse stromal cells. Nucleus is visualized by DAPI staining. (Scale bars, brightfield; H&E, 10 µm; IF, 2 µm in E.)
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