Transient left bundle branch block and intraventricular dyssynchrony as a cause of reversible left ventricular dysfunction: The "in vivo" documentation of spontaneous electrical remodeling
- PMID: 31141243
- PMCID: PMC6931411
- DOI: 10.1111/anec.12667
Transient left bundle branch block and intraventricular dyssynchrony as a cause of reversible left ventricular dysfunction: The "in vivo" documentation of spontaneous electrical remodeling
Abstract
Spontaneous resolution of non-rate-dependent left bundle branch block (LBBB) has been rarely reported. We present the case of a 74-year-old woman admitted with pulmonary edema, a newly diagnosed LBBB and severe left ventricular (LV) dysfunction. Five months later, the patient was asymptomatic, the ECG recording showed complete regression of the LBBB to narrow QRS and LV function completely recovered. However, at one-year follow-up LBBB reappeared together with mild LV dysfunction. Spontaneous resolution of LBBB may be responsible for LV electrical and mechanical reverse remodeling in dyssynchronopathies.
Keywords: ECG; dyssynchronopathy; heart failure; left bundle branch block.
© 2019 Wiley Periodicals, Inc.
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References
-
- Blanc, J. J. , Fatemi, M. , Bertault, V. , Baraket, F. , & Etienne, Y. (2005). Evaluation of left bundle branch block as a reversible cause of non‐ischaemic dilated cardiomyopathy with severe heart failure. A new concept of left ventricular dyssynchrony‐induced cardiomyopathy. Europace, 7(6), 604–610. 10.1016/j.eupc.2005.06005 - DOI - PubMed
-
- Caforio, A. L. , Pankuweit, S. , Arbustini, E. , Basso, C. , Gimeno‐Blanes, J. , Felix, S. B. , … Elliott, P. M. (2011). European Society of Cardiology working group on myocardial and pericardial diseases. Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: A position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. European Heart Journal, 34, 2636–2648. 10.1093/eurheartj/eht210 - DOI - PubMed
-
- Dizon, J. , Horn, E. , Neglia, J. , Medina, N. , & Garan, H. (2004). Loss of left bundle branch block follow biventricular pacing therapy for heart failure: Evidence for electrical remodelling? Journal of Interventional Cardiac Electrophysiology, 10, 47–50. 10.1023/B:JICE.0000011484.61659.b1 - DOI - PubMed
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